528862-00-2

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dihydro-1H-indole-3-carboxylic acid methyl ester is used as an intermediate in the production of drugs, particularly for the synthesis of antipsychotics and antidepressants. Its unique chemical structure and properties make it a valuable component in the development of new pharmaceutical products.
Used in Organic Chemistry:
2,3-Dihydro-1H-indole-3-carboxylic acid methyl ester is also utilized in the synthesis of various organic compounds, further expanding its applications in the field of chemistry. Its versatility as a building block allows for the creation of a wide range of molecules with potential applications in various industries.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 942-24-5 3-methoxycarbonylindole 
• 338760-26-2 methyl 1-tert-butoxycarbonyl-1H-indole-3-carboxylate 

Downstream Products

• 528861-99-6 methyl 1-formylindoline-3-carboxylate 
• 1268603-37-7 indolin-3-yldiphenylmethanol 
• 1268603-21-9 3-[(tert-butyldimethylsilyloxy)diphenylmethyl]indoline 
• 1268603-22-0 3-[diphenyl(trimethylsilyloxy)]methyl-indoline 
• 1268603-30-0 C₂₆H₂₇NO 
• 177201-79-5 2,3-dihydro-indole-1,3-dicarboxylic acid 1-tert-butyl ester 

Relevant academic research and scientific papers

FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS

The present invention relates to compounds of formulae I and H, or pharmaceutically acceptable salts or esters thereof. Further aspects of the invention relate to pharmaceutical compositions and therapeutic uses of said compounds in the treatment of diseases of uncontrolled cell growth, proliferation and/or survival, inappropriate cellular immune responses, inappropriate cellular inflammatory responses, or neurodegenerative disorders, preferably tauopathies, even more preferably, Alzheimer's disease.

Indoline-3-carboxylic acid derived organocatalysts for the anti-mannich reaction

Mannich type reactions of a preformed aldimine with various carbonyl compounds were investigated with a series of functionalised indoline derivatives as catalysts: indoline-3-carboxylic acid, the diphenylcarbinol analogue and O-protected silyl ether analo

SUBSTITUTED INDOLE DERIVATIVES

The present invention relates to substituted indole derivatives having the general formula (I) which act on the ORL 1 receptor wherein A and B mutually independently denote CH2, C=O or SO2, X stands for indolyl, unsubstituted or mono- or polysubstituted; T stands for (CR5a-cR6a-c)n, n = 1, 2 or 3, and Q stands for (CR7a-cR8a-c)m, m = 0,1, 2 or 3, processes for the preparation thereof, medicinal products containing these compounds and the use of substituted indole derivatives for the preparation of medicinal products.

Substituted indole derivatives

Substituted indole derivatives, processes for the preparation thereof, medicinal products and pharmaceutical compositions containing these compounds and the use of substituted indole derivatives to treat pain and other conditions and for other medical purposes.

Unexpected products from the Fp2-catalyzed reductive cyclization of nitroaromatics bearing pendant unsaturation

A representative o-nitroenone (Z=O) was cyclized by reduction with CO and [CpFe(CO)2]2 (Fp2) as the catalyst to give the corresponding 4-quinolone. In contrast, Baylis-Hillman adducts derived from o-nitrobenzaldehydes were