338760-26-2

Basic information

• Product Name: INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER
• Synonyms: INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER;METHYL 1-BOC-1H-INDOLE-3-CARBOXYLATE;1H-Indole-1,3-dicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester;1-tert-Butyl 3-Methyl 1H-indole-1,3-dicarboxylate
• CAS NO: 338760-26-2
• Molecular Formula: C₁₅H₁₇NO₄
• Molecular Weight: 275.3
• Mol File: 338760-26-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER(338760-26-2)
• EPA Substance Registry System: INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER(338760-26-2)

Safety Data

• Hazardous Substances Data: 338760-26-2(Hazardous Substances Data)

Usage

General Description

INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER is a chemical compound that is a derivative of indole-1,3-dicarboxylic acid. It is formed by the esterification of the carboxylic acid groups with tert-butanol and methyl alcohol. INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various bioactive molecules. It may also have potential applications in the development of new drugs or pharmaceutical products. However, further research is needed to fully understand the potential uses and properties of IND0LE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER.

Upstream product

• 942-24-5 3-methoxycarbonylindole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 67-56-1 methanol 
• 57476-50-3 1-tert-butoxycarbonyl-3-formylindole 
• 201230-82-2 carbon monoxide 
• 192189-07-4 tert-butyl 3-iodo-1H-indol-1-carboxylate 
• 609818-73-7 methyl 2-(4-methylphenoxy)-1-tert-butoxycarbonyl-1-H-indole-3-carboxylate 

Downstream Products

• 528862-00-2 methyl 1-(tert-butoxycarbonyl)indoline-3-carboxylate 
• 942-24-5 3-methoxycarbonylindole 
• 1383532-74-8 tert-butyl 3-(3-ethoxy-3-oxopropanoyl)-1H-indole-1-carboxylate 
• 141-97-9 ethyl acetoacetate 
• 1268603-30-0 C₂₆H₂₇NO 
• 1268603-22-0 3-[diphenyl(trimethylsilyloxy)]methyl-indoline 
• 1268603-21-9 3-[(tert-butyldimethylsilyloxy)diphenylmethyl]indoline 
• 1268603-37-7 indolin-3-yldiphenylmethanol 
• 96551-22-3 t-butyl 3-hydroxymethylindole-1-carboxylate 

Relevant articles and documents

Efficient and expeditious chemoselective BOC protection of amines in catalyst and solvent-free media

A green and eco-friendly route for the almost quantitative BOC protection of a large variety of aliphatic and aromatic amines, amino acids, and amino alcohols is reported in catalyst and solvent-free media under mild reaction conditions. The products were confirmed by 1H, 13C NMR, IR spectroscopy, and in some cases, elemental analysis. This protocol does not require any water quenches, solvent separations, and purification steps, such as recrystallization and column chromatography.

An efficient one-pot oxidative esterification of aldehydes to carboxylic esters using B(C6F5)3-TBHP

A simple and efficient protocol for oxidative esterification of diverse aldehydes with alcohols was accomplished with tert-butyl hydroperoxide and 1 mol % of tris(pentafluorophenyl)borane [B(C6F5)3] to generate the corresponding esters in good to excellent yields. The present protocol represents compatibility with wide range of functional groups as well as exceptional tolerance toward acid labile protecting groups such as TBDPS, TBDMS, acetonide, and Boc.

Microwave-assisted synthesis of 3-substituted indoles via intramolecular arene-alkene coupling of o-iodoanilino enamines

A generally applicable and high-yielding protocol for the synthesis of 3-substituted indole derivatives is described. Key features include microwave-assisted intramolecular arene-alkene coupling of o-iodoanilino enamines, and expedient synthesis of o-iodo