52909-94-1

Basic information

• Product Name: 2-(3,4-DICHLORO-PHENYL)-OXIRANE
• Synonyms: 2-(3,4-DICHLORO-PHENYL)-OXIRANE;Oxirane, 2-(3,4-dichlorophenyl)-
• CAS NO: 52909-94-1
• Molecular Formula: C₈H₆Cl₂O
• Molecular Weight: 189.04
• Mol File: 52909-94-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 264.2°Cat760mmHg
• Flash Point: 142.6°C
• Appearance: /
• Density: 1.428g/cm³
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-(3,4-DICHLORO-PHENYL)-OXIRANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DICHLORO-PHENYL)-OXIRANE(52909-94-1)
• EPA Substance Registry System: 2-(3,4-DICHLORO-PHENYL)-OXIRANE(52909-94-1)

Safety Data

• Hazardous Substances Data: 52909-94-1(Hazardous Substances Data)

Usage

General Description

2-(3,4-Dichloro-phenyl)-oxirane is a chemical compound with the molecular formula C8H6Cl2O. It is an epoxide, also known as a cyclic ether, with two chlorine atoms attached to a benzene ring. 2-(3,4-DICHLORO-PHENYL)-OXIRANE is commonly used in the synthesis of pharmaceuticals and organic chemicals. It has also been studied for its potential use in agricultural applications as a fungicide. Due to its reactive nature, it is important to handle and store 2-(3,4-Dichloro-phenyl)-oxirane with caution and in accordance with safety guidelines.

InChI:InChI=1/C8H6Cl2O/c9-6-2-1-5(3-7(6)10)8-4-11-8/h1-3,8H,4H2

Upstream product

• 2632-10-2 2-bromo-1-(3,4-dichlorophenyl)ethanone 
• 2039-83-0 3,4-dichlorostyrene 
• 2642-63-9 3',4'-dichloroacetophenone 
• 1475-11-2 1-(3,4-dichlorophenyl)ethan-1-ol 

Downstream Products

• 18970-70-2 2-[2-(2-Chloro-phenyl)-ethylamino]-1-(3,4-dichloro-phenyl)-ethanol 
• 30332-45-7 2-diethylamino-1-(3,4-dichloro-phenyl)-ethanol 
• 5402-86-8 2-dibutylamino-1-(3,4-dichloro-phenyl)-ethanol 
• 2971-04-2 2-Diallylamino-1-<3,4-dichlor-phenyl>-aethanol 
• 30332-47-9 2-dibenzylamino-1-(3,4-dichloro-phenyl)-ethanol 
• 19045-46-6 1-(3,4-Dichloro-phenyl)-2-[2-(3,4-dichloro-phenyl)-2-hydroxy-ethylamino]-ethanol 
• 1475-11-2 1-(3,4-dichlorophenyl)ethan-1-ol 
• 35364-79-5 2-(3,4-dichlorophenyl)ethanol 
• 103866-26-8 2-(3,4-dichlorophenyl)-2,3,5,6-tetrahydro-1H-imidazo<1,2-a>imidazole 
• 103866-13-3 1-(2-(3,4-dichlorophenyl)-2-hydroxyethyl)-2-iminoimidazolidine hydrobromide 
• 1095616-43-5 2-(3,4-dichlorophenyl)-2-hydroperoxyethanol 
• 586418-02-2 (R)-1-(3,4-dichlorophenyl)-1,2-ethanediol 

Relevant articles and documents

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ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF

Novel aryl, heteroaryl, and non-aromatic heterocyle substituted tetrahydroisoquinolines are described in the present invention. These compounds are used in the treatment of various neurological and physiological disorders. Methods of making these compounds are also described in the present invention.

N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H- indoline-3,4'-piperidine]: Vesamicol analogues with affinity for monoamine transporters

As part of our ongoing structure-activity studies of the vesicular acetylcholine transporter ligand 2-(4-phenylpiperidino)cyclohexanol [vesamicol, 1), 22 N-hydroxy(phenyl)alkyl derivatives of 3β-phenyltropane, 6, and 1-methylspiro[1H-indoline-3,4'-piperidine], 7, were synthesized and tested for binding in vitro. Although a few compounds displayed moderately high affinity for the vesicular acetylcholine transporter, no compound was more potent than the prototypical vesicular acetylcholine transporter ligand vesamicol. However, a few derivatives of 6 displayed higher affinity for the dopamine transporter than cocaine. We conclude that modification of the piperidyl fragment of 1 will not lead to more potent vesicular acetylcholine transporter ligands.