52914-23-5

Basic information

• Product Name: 4-Iodophenethyl alcohol
• Synonyms: 4-Iodobenzeneethanol;4-Iodophenethyl alcohol;4-Iodophenylethylalcohol;Benzeneethanol, 4-iodo-;Brn 1933621;Phenethyl alcohol, p-iodo-;p-Iodophenethyl alcohol;2-(4-iodophenyl)ethan-1-ol
• CAS NO: 52914-23-5
• Molecular Formula: C₈H₉IO
• Molecular Weight: 248.06
• Mol File: 52914-23-5.mol
• Article Data: 15

Chemical Properties

• Melting Point: 48-49℃
• Boiling Point: 276℃
• Flash Point: 121℃
• Appearance: /
• Density: 1.749
• Vapor Pressure: 0.00242mmHg at 25°C
• Refractive Index: 1.626
• Storage Temp.: 2-8°C(protect from light)
• PKA: 14.79±0.10(Predicted)
• CAS DataBase Reference: 4-Iodophenethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodophenethyl alcohol(52914-23-5)
• EPA Substance Registry System: 4-Iodophenethyl alcohol(52914-23-5)

Safety Data

• Hazardous Substances Data: 52914-23-5(Hazardous Substances Data)

Usage

General Description

4-Iodophenethyl alcohol, also known as 4-Iodo-2-phenylethanol, is a chemical compound with the molecular formula C8H9IO. It is a colorless to pale yellow liquid with a slightly floral odor. 4-Iodophenethyl alcohol is commonly used as a fragrance ingredient and flavoring agent in various consumer products. It is also used in the synthesis of other chemical compounds, including pharmaceuticals and organic synthesis. 4-Iodophenethyl alcohol has antibacterial and antifungal properties, making it useful in pharmaceutical and personal care products. Additionally, it is utilized in the production of insect repellents and can be found in some perfumes and colognes.

InChI:InChI=1/C8H9IO/c9-8-3-1-7(2-4-8)5-6-10/h1-4,10H,5-6H2

Upstream product

• 17961-95-4 4-Amino-1-(2-trimethylsilyl-aethyl)-benzol 
• 75867-38-8 4-nitro-1-(trimethylsilylethynyl)benzene 
• 586-78-7 para-nitrophenyl bromide 
• 4654-39-1 4-bromophenethanol 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 60-12-8 2-phenylethanol 
• 103-82-2 phenylacetic acid 
• 103-45-7 acetic acid phenethyl ester 
• 1798-06-7 (4-iodophenyl)acetic acid 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 
• 101251-45-0 4-(2-hydroxy-ethyl)-phenylmercury ⁽¹⁺⁾; chloride 

Downstream Products

• 162358-06-7 4-octylphenethyl methanesulfonate 
• 162358-05-6 2-(4-Octylphenyl)ethyl alcohol 
• 162358-07-8 2-(4-octylphenyl)-1-iodoethane 
• 858677-87-9 4-iodophenethyl methanesulfonate 
• 1510847-52-5 S-4-(((9s,10s)-11-(4-(2-(acetylthio)ethyl)phenyl)-12-(anthracen-9-yl)-9,10-dihydro-9,10-ethenoanthracen-9-yl)ethynyl)phenethyl ethanethioate 
• 1510847-49-0 S-(4-(anthracen-9-ylethynyl)phenethyl) ethanethioate 
• 1510847-48-9 S-[2-(4-iodophenyl)ethyl]thioacetate 
• 1222139-10-7 3-[4-[2-(benzyloxy)ethyl]phenyl]-5-[[1-(tert-butoxycarbonyl)-2(S)-azetidinyl]methoxy]pyridine 
• 865488-97-7 2-(p-iodophenyl)ethyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->2)-α-D-mannopyranosyl-(1->6)-β-D-glucopyranoside 
• 865488-96-6 2-(p-iodophenyl)ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->2)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl-(1->6)-2,3,4-tri-O-acetyl-β-D-glucopyranoside 
• 865488-94-4 2-(4-iodophenyl)ethyl 2,3,4-tri-O-acetyl-β-D-glucopyranoside 
• 1357000-54-4 2-(p-iodophenyl)ethyl 2,3,4-tri-O-acetyl-6-O-allyloxycarbonyl-β-D-glucopyranoside 
• 73918-57-7 p-Iodophenylethylamine 
• 1333307-95-1 C₅₃H₈₇NO₄ 

Relevant articles and documents

Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists

A series of benzimidazoles (4) was synthesized and evaluated in vitro as potent and selective NPY Y1 receptor antagonists. Substitution of the piperidine nitrogen of 4 with appropriate R groups resulted in compounds with more than 80-fold higher affinity

Iodinated Choline Transport-Targeted Tracers

We present a novel series of radioiodinated tracers and potential theranostics for diseases accompanied by pathological function of proteins involved in choline transport. Unlike choline analogues labeled with 11C or 18F that are currently used in the clinic, the iodinated compounds described herein are applicable in positron emission tomography, single-photon emission computed tomography, and potentially in therapy, depending on the iodine isotope selection. Moreover, favorable half-lives of iodine isotopes result in much less challenging synthesis by isotope exchange reaction. Six of the described compounds were nanomolar ligands, and the best compound possessed an affinity 100-fold greater than that of choline. Biodistribution data of 125I-labeled ligands in human prostate carcinoma bearing (PC-3) mice revealed two compounds with a biodistribution profile superior to that of [18F]fluorocholine.

Support curvature and conformational freedom control chemical reactivity of immobilized species

We show that bimolecular reactions between species confined to the surfaces of nanoparticles can be manipulated by the nature of the linker, as well as by the curvature of the underlying particles.