53008-62-1Relevant articles and documents
Reactivity of glycopyranosyl trichloroacetimidates with air-oxidised samarium diiodide in tetrahydrofuran
Adinolfi, Matteo,Barone, Gaspare,Iadonisi, Alfonso,Lanzetta, Rosa
, p. 5605 - 5608 (1998)
Glycopyranosyl trichloroacetimidates react with SmI2/O2/THF to give 4- iodo-n-butyl 1,2-transglycopyranosides. Good to high yields can be obtained from 2α-O-acylated trichloroacetimidates. With armed or manno substrates competitive f
Stereoselective Synthesis of 1,2-cis-Glycosyl Sulfones and Their Application in One-Pot Julia Olefination for the Synthesis of exo-Glycals
Oka, Natsuhisa,Suzuki, Kanna,Mori, Ayumi,Ando, Kaori
, p. 5922 - 5933 (2021/11/22)
Glycosyl sulfones are important intermediates in the synthesis of various sugar derivatives. However, their 1,2-cis-isomers have not been extensively studied because of lower availability. Herein, we report the highly stereoselective synthesis of heteroar
Alpha-galactosylceramide analogs, a preparation method thereof, and a pharmaceutical composition for treatment and prevention of diseases by abnormal immune modulation comprising the same
-
Paragraph 0104; 0133-0136, (2019/07/10)
The present invention refers to alpha - ceramide analogs, including manufacturing method of immunomodulatory or pharmaceutical composition for treating or preventing diseases caused and relates to, more particularly NKT intracellular Th1 or selective activation reaction Th2 can be effective for treating or preventing diseases caused immunomodulatory or alpha - ceramide analogs, and manufacturing method of including a pharmaceutical composition for treating or preventing diseases caused immunomodulatory or more are disclosed. (by machine translation)
Synthesis and biological evaluation of α-galactosylceramide analogues with heteroaromatic rings and varying positions of a phenyl group in the sphingosine backbone
Kim, Yongju,Oh, Keunhee,Song, Heebum,Lee, Dong-Sup,Park, Seung Bum
, p. 7100 - 7109 (2013/10/01)
We designed and synthesized seven α-GalCer analogues with a pyrazole moiety and varying positions of a phenyl group in the sphingosine backbone to polarize cytokine secretion. On the basis of in vitro and in vivo biological evaluations, we found that anal