530740-47-7

Usage

Uses

1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone is used as a chemical intermediate in the synthesis of various organic compounds. Its unique structure, which includes a chloro group, a hydroxy group, a naphthalene moiety, and a ketone group, makes it a versatile building block for the creation of a range of chemical products.
Used in Pharmaceutical Industry:
1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone is used as a key component in the development of pharmaceuticals, particularly in the synthesis of drugs that target specific biological pathways or receptors. Its structural diversity allows for the creation of molecules with tailored properties, such as improved bioavailability or enhanced efficacy.
Used in Chemical Research:
1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone is used as a research tool in academic and industrial laboratories. Its complex structure provides a platform for studying the effects of different functional groups on chemical reactivity and stability, contributing to the broader understanding of organic chemistry.
Used in Material Science:
1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone is used as a precursor in the development of new materials with specific properties, such as improved thermal stability or enhanced electrical conductivity. Its incorporation into polymers or other materials can lead to the creation of novel composites with unique characteristics.
Used in Environmental Applications:
1-(4-Chloro-1-hydroxy-naphthalen-2-yl)-ethanone is used in the remediation of contaminated environments, such as soil or water, where its chemical properties can be leveraged to bind or neutralize pollutants. Its versatility in chemical reactions makes it a candidate for the development of new environmental treatment strategies.

Upstream product

• 604-44-4 4-chloronaphthalen-1-ol 
• 75-36-5 acetyl chloride 
• 7791-25-5 sulfuryl dichloride 
• 60-29-7 diethyl ether 
• 711-79-5 1-hydroxy-2-acetonaphthone 
• 53422-20-1 4-chloronaphthalen-1-yl acetate 
• 860538-80-3 bis-(3-acetyl-4-hydroxy-[1]naphthyl)-sulfide 
• 71-43-2 benzene 
• 36441-29-9 14-phenyl-14H-dibenzo[a.j]xanthene 
• 64-19-7 acetic acid 

Downstream Products

• 1312683-36-5 N-{1-[4-chloro-1-(3-fluorophenyl)-2-naphthyl]ethyl}-9H-purin-6-amine 
• 1312685-87-2 1-[4-chloro-1-(3-fluorophenyl)-2-naphthyl]ethanamine 
• 1312685-86-1 1-[4-chloro-1-(3-fluorophenyl)-2-naphthyl]ethanone 
• 1312683-33-2 1-{4-chloro-2-[1-(9H-purin-6-ylamino)ethyl]-1-naphthyl}piperidin-4-ol 
• 1312685-85-0 1-[2-(1-aminoethyl)-4-chloro-1-naphthyl]piperidin-4-ol 
• 1312685-84-9 1-[4-chloro-1-(4-hydroxypiperidin-1-yl)-2-naphthyl]ethanone 
• 1312685-83-8 2-acetyl-4-chloro-1-naphthyl trifluoromethanesulfonate 

Relevant academic research and scientific papers

SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS

The present invention provides fused aryl and heteroaryl derivatives of Formula I that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases

Bismuth triflate-catalyzed fries rearrangement of aryl acetates

Bismuth triflate was found to be an efficient catalyst in the Fries rearrangement of phenyl or 1-naphthyl acetates. Both reactions proceeded smoothly with a catalytic amount of bismuth triflate (10 mol%) to afford the corresponding hydroxyaryl ketone in moderate to good yields in most cases.

Titanium(IV) chloride-mediated ortho-acylation of phenols and naphthols

The use of titanium(IV) chloride as a Lewis acid for direct ortho-acylation of phenols and naphthols proves to be a convenient, more general and direct route to various hydroxyaryl ketones. The route is regioselective, leading to ortho C-acylated products in satisfactory to high yields in most cases.

Photochromic spiropyran compounds

A series of novel photochromic spiropyrans are disclosed in which a spiro-adamantane group is introduced into the 2-position of the benzopyran or naphthopyran ring. The spiropyran compounds of the invention exhibit heliochromic properties, i.e. they color in sunlight and fade rapidly at ambient temperatures in the absence of U.V. light, making them good candidates for use in the manufacture of sunglasses. The invention includes lenses which darken in sunlight and incorporate the novel spiropyrans and a process for the preparation of the spiropyran compounds.