531508-32-4 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
Methyl 2,2-difluoro-1,3-benzodioxole-4-carboxylate serves as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique chemical structure allows for the creation of diverse compounds with specific therapeutic or pesticidal properties.
Used in Fragrance and Flavor Production:
methyl 2,2-difluoro-1,3-benzodioxole-4-carboxylate is utilized in the production of fragrances and flavoring agents, enhancing the sensory qualities of various consumer products. Its ability to impart distinct scents and tastes makes it a valuable ingredient in the fragrance and flavor industries.
Used in Anticancer Research:
Methyl 2,2-difluoro-1,3-benzodioxole-4-carboxylate has been studied for its potential as an anti-cancer agent. Its biological activities are of interest to researchers exploring new avenues for cancer treatment, with the aim of developing more effective therapies for various types of cancer.
Used in Organic Chemistry Research:
As a compound with unique structural features, methyl 2,2-difluoro-1,3-benzodioxole-4-carboxylate is employed in organic chemistry research to investigate its properties and potential applications. This research can lead to the discovery of new chemical reactions and the development of novel compounds with specific functions in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 531508-32-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,1,5,0 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 531508-32:
(8*5)+(7*3)+(6*1)+(5*5)+(4*0)+(3*8)+(2*3)+(1*2)=124
124 % 10 = 4
So 531508-32-4 is a valid CAS Registry Number.
531508-32-4Relevant academic research and scientific papers
Schlosser, Manfred,Gorecka, Joanna,Castagnetti, Eva
, p. 452 - 462 (2003)
The conversion of 2,2-difluoro-1,3-benzodioxole, an exceptionally acidic arene, via a 4-lithiated intermediate into more than three dozen new derivatives was conceived as a case study. The lithiated species was trapped by C0-electrophiles (4-toluenesulfonyl azide, fluorodimethoxyborane, iodine), C1-electrophiles (carbon dioxide, N,N-dimethylformamide, formaldehyde, dimethyl sulfate), C2-electrophiles (oxalic acid diesters, oxirane), C3-electrophiles (oxetane), and higher alkyl iodides. The resulting carboxylic acid 1a may be treated with organolithium compounds to afford ketones (e.g. 10) and the aldehyde 9 can be condensed with nitromethane or acetic anhydride under basic conditions. If not oxidized with chromium trioxide to the corresponding carboxylic acids, the alcohols 2b, 2c, and 2d can be transformed into the corresponding bromides (12) or sulfonates (13). Their condensation with nitrogen-containing C0-nucleophiles (hydroxylamine, sodium azide, potassium phthalimide), C1-nucleophiles (potassium cyanide), and C2-nucleophiles (aceto-nitrile) opens a convenient access to the amines 3. Other reactions gave, despite a proven track record in other areas, only moderate yields. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
