531508-46-0 Usage
Uses
Used in Organic Synthesis:
4-AminoMethyl-2,2-difluor... is used as a key intermediate in the synthesis of functionalized 2,2-Difluoro-1,3-benzodioxoles. It serves as a versatile building block for the preparation of a wide range of chemical compounds with diverse properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-AminoMethyl-2,2-difluor... is used as a starting material for the development of new drugs and drug candidates. Its unique structure and functional groups make it a promising candidate for the design of novel therapeutic agents with improved pharmacological properties.
Used in Chemical Research:
4-AminoMethyl-2,2-difluor... is also used in chemical research to study the reactivity and properties of various functional groups. Researchers utilize 4-AMinoMethyl-2,2-difluor... to explore new reaction pathways and develop innovative synthetic methods for the preparation of complex organic molecules.
Used in Material Science:
In the field of material science, 4-AminoMethyl-2,2-difluor... is employed in the development of new materials with specific properties. Its unique structure and functional groups can be utilized to create materials with tailored characteristics, such as improved stability, reactivity, or selectivity, for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 531508-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,1,5,0 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 531508-46:
(8*5)+(7*3)+(6*1)+(5*5)+(4*0)+(3*8)+(2*4)+(1*6)=130
130 % 10 = 0
So 531508-46-0 is a valid CAS Registry Number.
531508-46-0Relevant academic research and scientific papers
A homologous series of O- and N-functionalized 2,2-difluoro-1,3-benzodioxoles: An exercise in organometallic methodology
Schlosser, Manfred,Gorecka, Joanna,Castagnetti, Eva
, p. 452 - 462 (2007/10/03)
The conversion of 2,2-difluoro-1,3-benzodioxole, an exceptionally acidic arene, via a 4-lithiated intermediate into more than three dozen new derivatives was conceived as a case study. The lithiated species was trapped by C0-electrophiles (4-toluenesulfonyl azide, fluorodimethoxyborane, iodine), C1-electrophiles (carbon dioxide, N,N-dimethylformamide, formaldehyde, dimethyl sulfate), C2-electrophiles (oxalic acid diesters, oxirane), C3-electrophiles (oxetane), and higher alkyl iodides. The resulting carboxylic acid 1a may be treated with organolithium compounds to afford ketones (e.g. 10) and the aldehyde 9 can be condensed with nitromethane or acetic anhydride under basic conditions. If not oxidized with chromium trioxide to the corresponding carboxylic acids, the alcohols 2b, 2c, and 2d can be transformed into the corresponding bromides (12) or sulfonates (13). Their condensation with nitrogen-containing C0-nucleophiles (hydroxylamine, sodium azide, potassium phthalimide), C1-nucleophiles (potassium cyanide), and C2-nucleophiles (aceto-nitrile) opens a convenient access to the amines 3. Other reactions gave, despite a proven track record in other areas, only moderate yields. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
