53207-59-3

Basic information

• Product Name: 2-Methyl-1-[4-(Methylsulfonyl)phenyl]-1-propanone
• Synonyms: 2-Methyl-1-[4-(Methylsulfonyl)phenyl]-1-propanone;p-Methylsulfonylisobutyrophenone
• CAS NO: 53207-59-3
• Molecular Formula: C₁₁H₁₄O₃S
• Molecular Weight: 226.29206
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 53207-59-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Solubility: Acetone, Chloroform, Ethyl Acetate
• CAS DataBase Reference: 2-Methyl-1-[4-(Methylsulfonyl)phenyl]-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-1-[4-(Methylsulfonyl)phenyl]-1-propanone(53207-59-3)
• EPA Substance Registry System: 2-Methyl-1-[4-(Methylsulfonyl)phenyl]-1-propanone(53207-59-3)

Safety Data

• Hazardous Substances Data: 53207-59-3(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

2-Methyl-1-[4-(methylsulfonyl)phenyl]-1-propanone (cas# 53207-59-3) is a compound useful in organic synthesis.

Upstream product

• 99059-63-9 1-(4-iodophenyl)-2-methyl-1-propanone 
• 67-68-5 dimethyl sulfoxide 
• 49660-93-7 4'-bromoisobutyrophenone 
• 20277-69-4 sodium methansulfinate 
• 10342-83-3 4'-Bromopropiophenone 
• 67-56-1 methanol 
• 10297-73-1 4-(methanesulfonyl)acetophenone 
• 100-68-5 methyl-phenyl-thioether 
• 53207-58-2 2-methyl-1-(4-(methylthio)phenyl)-propan-1-one 

Downstream Products

• 189955-89-3 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one 
• 189954-96-9 3-(Cyclopropylmethoxy)-5.5-dimethyl-4-(4-(methylsulfonyl)phenyl)-5H-furan-2-one 
• 180048-73-1 2-hydroxy-2-methyl-1-(4-(methylsulfonyl)-phenyl)propan-1-one 
• 189955-79-1 2-bromo-2-methyl-1-[4-(methylsulfonyl)phenyl]propan-1-one 

Relevant articles and documents

Synthesis methods of firocoxib and firocoxib intermediate

The invention relates to the field of medicine synthesis and provides synthesis methods of firocoxib and a firocoxib intermediate. The synthesis method of the firocoxib intermediate takes 4'-bromopropiophenone as a starting raw material and a condition th

Methylation of C(sp3)-H/C(sp2)-H bonds with methanol catalyzed by cobalt system

A highly efficient Co-based catalytic system, composed of a commercially available Co salt, a tetradentate phosphine ligand P-(CH2CH2PPh2)3(PP3), and a base (denoted as [Co]/PP3/base), is developed for the methylation of C(sp3)-H and C(sp2)-H bonds using methanol as a methylating reagent. The Co(BF4)2.6H2O/PP3/K2CO3 catalytic system showed high catalytic activity for the methylation of C-H bonds in aryl alkyl ketones, aryl acetonitriles, and indoles, with wide substrate scope and good functional group tolerance, and methylsubstituted products were obtained in good to excellent yields at 100 °C. This cheap, readily available, and highly efficient Co-based catalytic system may have promising applications in methylation reaction using methanol.