53218-10-3

Basic information

• Product Name: 4-Nitrobenzoic acid 4-methoxybenzyl ester
• Synonyms: 4-Nitrobenzoic acid 4-methoxybenzyl ester
• CAS NO: 53218-10-3
• Molecular Formula: C₁₅H₁₃NO₅
• Molecular Weight: 287.27
• Mol File: 53218-10-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Nitrobenzoic acid 4-methoxybenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitrobenzoic acid 4-methoxybenzyl ester(53218-10-3)
• EPA Substance Registry System: 4-Nitrobenzoic acid 4-methoxybenzyl ester(53218-10-3)

Safety Data

• Hazardous Substances Data: 53218-10-3(Hazardous Substances Data)

Upstream product

• 619-50-1 4-nitrobenzoic acid methyl ester 
• 15175-54-9 N,N-dimethyl-4-methoxylbenzylamine 
• 555-16-8 4-nitrobenzaldehdye 
• 105-13-5 4-Methoxybenzyl alcohol 
• 121-98-2 methyl 4-methoxybenzoate 
• 122-04-3 4-nitro-benzoyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 99-81-0 4-Nitrophenacyl bromide 
• 25407-30-1 4-nitrophenacylpyridinium bromide 
• 62-23-7 4-nitro-benzoic acid 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 446867-23-8 4-methoxybenzyl 2,2,2-trifluoroethyl ether 
• 127866-65-3 5-[(4-methoxybenzyl)sulfanyl]-1-phenyl-1H-tetrazole 
• 62-23-7 4-nitro-benzoic acid 

Relevant articles and documents

Vitamin B1-catalyzed aerobic oxidative esterification of aromatic aldehydes with alcohols

A straightforward aerobic oxidative esterification of aryl aldehydes with alcohols has been developed for the synthesis of substituted esters by employing vitamin B1 as a cost-effective, metal-free, and eco-friendly NHC catalyst. Air is used as a green terminal oxidant. The reaction is a useful addition to the existing NHC-catalytic oxidative esterification.

A metal-free approach for the synthesis of amides/esters with pyridinium salts of phenacyl bromides via oxidative C–C bond cleavage

An efficient, simple, and metal-free synthetic approach for the N- and O-benzoylation of various amines/benzyl alcohols with pyridinium salts of phenacyl bromides is demonstrated to generate the corresponding amides and esters. This protocol facilitates the oxidative cleavage of a C–C bond followed by formation of a new C–N/C–O bond in the presence of K2CO3. Various pyridinium salts of phenacyl bromides can be readily transformed into a variety of amides and esters which is an alternative method for the conventional amidation and esterification in organic synthesis. High functional group tolerance, broad substrate scope and operational simplicity are the prominent advantages of the current protocol.

Proton-exchanged montmorillonite-mediated reactions of methoxybenzyl esters and ethers

Proton-exchanged montmorillonite (H-mont) was found to be an eco-friendly and cost-effective catalyst for the generation of O-methylated quinone methides (QM) from the corresponding p or o-methoxybenzyl esters and ethers. Nucleophilic trapping of the O-methylated QM with arenes, alcohols, 1,3-dicarbonyl compounds, silyl enol ethers, and allylsilanes has been carried out, respectively, leading to eco-friendly benzylation reactions. Using this protocol, H-mont-mediated deprotection of PMB-protected esters and ethers have been realized for the first time. This work would pave the way for further exploration in O-alkylated QM that are of chemical and biological significance.