5323-75-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Benzoyl-2,3-dihydro-1H-inden-1-one is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into various drug molecules.
Used in Fragrance Industry:
It is used as an intermediate in the synthesis of fragrances due to its slightly floral odor, contributing to the creation of various scent profiles.
Used in Dye and Pigment Production:
2-Benzoyl-2,3-dihydro-1H-inden-1-one is used in the production of dyes and pigments, where its chemical structure allows for the development of colorants for different applications.
Used in Polymer Industry:
It serves as a component in the synthesis of polymers, where its cyclic ketone structure can be utilized to create specific polymer properties.
Safety Note:
It is important to handle 2-benzoyl-2,3-dihydro-1H-inden-1-one with care, as it may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Proper safety measures should be taken during its use in various industrial processes.

Upstream product

• 83-33-0 inden-1-one 
• 56409-75-7 ethyl 2-benzyl-3-oxo-3-phenylpropanoate 
• 98-86-2 acetophenone 
• 98-88-4 benzoyl chloride 
• 577-16-2 2-Methylacetophenone 
• 61001-54-5 2-methyldibenzoylmethane 
• 50454-22-3 methyl (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)benzoate 
• 62322-80-9 2-(2-Benzoylvinyl)benzoesaeure 
• 119-67-5 o-carboxybenzaldehyde 
• 40400-13-3 2-Iodobenzyl bromide 
• 201230-82-2 carbon monoxide 
• 153974-34-6 3-(2-iodophenyl)-1-phenylpropan-1-one 
• 643-79-8 o-phthalic dicarboxaldehyde 

Downstream Products

• 21012-53-3 1,3-diphenyl-4H-indeno[2,3-d]pyrazole 
• 83-33-0 inden-1-one 
• 65-85-0 benzoic acid 
• 1204747-37-4 C₂₀H₁₃N₃O₂S 
• 16003-58-0 3-Phenyl-2,4-dihydroindeno<1,2,c>pyrazol 
• 55849-38-2 (E)-2-(1-Acetoxybenzyliden)-1-indanon 
• 18398-39-5 Essigsaeure-(2-benzoyl-3-indenylester) 
• 102012-62-4 4-[2-(3-oxo-3-phenyl-propyl)-benzoyl]-morpholine 

Relevant academic research and scientific papers

Rhodium-Catalyzed Aerobic Decomposition of 1,3-Diaryl-2-diazo-1,3-diketones: Mechanistic Investigation and Application to the Synthesis of Benzils

The conversion of 1,3-diaryl-2-diazo-1,3-diketones to 1,2-daryl-1,2-diketones (benzils) is reported based on a rhodium(II)-catalyzed aerobic decomposition process. The reaction occurs at ambient temperatures and can be catalyzed by a few dirhodium carboxylates (5 mol %) under a balloon pressure of oxygen. Moreover, an oxygen atom from the O2 reagent is shown to be incorporated into the product, and this is accompanied by the extrusion of a carbonyl unit from the starting materials. Mechanistically, it is proposed that the decomposition may proceed via the interaction of a ketene intermediate resulting from a Wolff rearrangement of the carbenoid, with a rhodium peroxide or peroxy radical species generated upon the activation of molecular oxygen. The proposed mechanism has been supported by the results from a set of controlled experiments. By using this newly developed strategy, a large array of benzil derivatives as well as 9,10-phenanthrenequinone were synthesized from the corresponding diazo substrates in varying yields. On the other hand, the method did not allow the generation of benzocyclobutene-1,2-dione from 2-diazo-1,3-indandione because of the difficulty of inducing the initial rearrangement.

METHOD FOR PREPARING 1,3-DICARBONYL COMPOUND BASED ON METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM

Disclosed is a method for preparing a 1,3-dicarbonyl compound based on a metal hydride/palladium compound system. The method includes the following steps: suspending a palladium compound and a metal hydride in a solvent under the protection of nitrogen, t

APPLICATION OF METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM IN PREPARATION OF 1,3-DICARBONYL COMPOUND IN CASCADE REACTION OF ELECTRON-DEFICIENT ALKENE COMPOUND

Provided is an application of a metal hydride/palladium compound system in the preparation of a 1,3-dicarbonyl compound in a cascade reaction of an electron-deficient alkene compound, said reaction comprising the following steps: under the protection of n

The Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed Reductions of α, β-Unsaturated Carbonyl Compounds

Sodium hydride was employed as a Michael donor under the catalysis of PdCl2 for 1,4-conjugate reductions of α, β-unsaturated carbonyl compounds, which features operational simplicity, mild conditions and high atom-economy. The merits of NaH as a reductant were demonstrated by the one-pot or cascade reactions for the syntheses of complex molecules. (Figure presented.).

Method for preparing 1,3-dicarbonyl compound based on metal hydride/palladium compound system

The invention discloses a method for preparing a 1,3-dicarbonyl compound based on a metal hydride/palladium compound system. The method comprises the following steps: making a palladium compound and metal hydride suspend in a solvent under the protection

Application of metal hydride/ palladium compound system in preparing 1,3-dicarbonyl compound through cascade reaction in electron-deficient alkene compound

The invention discloses application of a metal hydride/ palladium compound system in preparing a 1,3-dicarbonyl compound through cascade reaction in an electron-deficient alkene compound. The reactioncomprises the following steps of under the protection o

Gold-catalyzed ring-expansion through acyl migration to afford furan-fused polycyclic compounds

A gold-catalyzed ring-expansion reaction of alkynones to access furan-fused polycyclic compounds is reported. Mechanistic studies revealed that the reaction might occur through a tandem 1,2-acyl migration/Friedel-Crafts reaction.

SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists

We describe a medicinal chemistry approach for generating a series of 2-(1H-pyrazol-1-yl)thiazoles as EP1 receptor antagonists. To improve the physicochemical properties of compound 1, we investigated its structure-activity relationships (SAR).

Palladium-catalyzed carbonylative cyclization via trapping of acylpalladium derivatives with internal enolates. Its scope and factors affecting the C-to-O ratio

The Pd-catalyzed carbonylative cyclization reaction involving ω-acyl-substituted acylpalladium derivatives can proceed via intramolecular trapping with either C- or O-enolates; the preferential formation of either 5- or 6-membered rings dictates the C-to-