532440-88-3

Usage

Uses

Used in Pharmaceutical Industry:
2-bromo-5-methoxy-4-methylaniline serves as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs. Its specific chemical structure allows it to be a key component in the creation of medicinal compounds, enhancing their therapeutic effects and applications in treating various health conditions.
Used in Dye Industry:
In the dye industry, 2-bromo-5-methoxy-4-methylaniline is utilized for the production of dyes. Its chemical properties make it suitable for creating a range of colorants used in different applications, such as textiles, plastics, and printing inks, due to its ability to impart vibrant and stable colors.
Used in Agrochemical Industry:
2-bromo-5-methoxy-4-methylaniline also finds its application in the agrochemical sector, where it is used in the synthesis of various agrochemicals. Its role in this industry is crucial for developing products that can protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
As a building block in organic synthesis, 2-bromo-5-methoxy-4-methylaniline is employed to construct more complex organic molecules. Its versatility in chemical reactions allows for the creation of a wide array of compounds with diverse applications across various fields.
Used as a Reagent in Chemical Reactions:
Due to its reactivity and functional groups, 2-bromo-5-methoxy-4-methylaniline is used as a reagent in various chemical reactions. It facilitates the synthesis of other compounds and contributes to the advancement of chemical research and development.

Upstream product

• 144-55-8 sodium hydrogencarbonate 
• 16452-01-0 ortho-cresidine 

Downstream Products

• 1072895-84-1 2,4-dichloro-7-methoxy-6-methylquinazoline 

Relevant academic research and scientific papers

Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase

G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates. Although they are closely related, GLP and G9a possess distinct physiological and pathophysiological functions. Thus, GLP or G9a selective small-molecule inhibitors are useful tools to dissect their distinct biological functions. We previously reported potent and selective G9a/GLP dual inhibitors including UNC0638 and UNC0642. Here we report the discovery of potent and selective GLP inhibitors including 4 (MS0124) and 18 (MS012), which are >30-fold and 140-fold selective for GLP over G9a and other methyltransferases, respectively. The cocrystal structures of GLP and G9a in the complex with either 4 or 18 displayed virtually identical binding modes and interactions, highlighting the challenges in structure-based design of selective inhibitors for either enzyme.

TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF

A tetrazolinone compound represented by formula (1): wherein Q represents a 6-membered aromatic heterocyclic group optionally having one or more atoms or groups selected from Group P1, provided that a heteroatom constituting the heterocyclic gr

N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases

The present invention relates to certain compounds of Formula (I) which can be useful in the treatment of diseases, such as, cancer, metabolic disorders, Type 2 Diabetes, dyslipidemia and/or hyperchloesterolemia: