532935-93-6Relevant academic research and scientific papers
Synthesis and antitumor activity of 2-(m-substituted-benzoyl)baccatin III analogs from taxinine
Horiguchi, Tohru,Oritani, Takayuki,Kiyota, Hiromasa
, p. 1529 - 1538 (2003)
2-m-Azidobenzoyl and 2-m-chlorobenzoyl baccatin III analogs were prepared from taxinine, a major component in Japanese yew leaves. In this study, a novel acetyl migration from 13- to 4-hydroxyl group was observed. The antitumor activity of these compounds
Structure-activity relationships of some taxoids as multidrug resistance modulator
Hasegawa, Toshiaki,Bai, Jao,Zhang, Shujun,Wang, Jinlan,Matsubara, Junichi,Kawakami, Junichi,Tomida, Akihiro,Tsuruo, Takashi,Hirose, Katsutoshi,Sakai, Junichi,Kikuchi, Midori,Abe, Mariko,Ando, Masayoshi
, p. 1122 - 1126 (2008/01/27)
1,7-Deoxy-4-deacetylbaccatin III (12) and its five analogues 6-9, 13, and their oxetane ring opened derivatives 14, 16, and 17, which were synthesized from taxinine, showed significant activity as MDR reversal agent by the assay of the calcein accumulatio
