532935-96-9Relevant academic research and scientific papers
Structure-activity relationships of some taxoids as multidrug resistance modulator
Hasegawa, Toshiaki,Bai, Jao,Zhang, Shujun,Wang, Jinlan,Matsubara, Junichi,Kawakami, Junichi,Tomida, Akihiro,Tsuruo, Takashi,Hirose, Katsutoshi,Sakai, Junichi,Kikuchi, Midori,Abe, Mariko,Ando, Masayoshi
, p. 1122 - 1126 (2008/01/27)
1,7-Deoxy-4-deacetylbaccatin III (12) and its five analogues 6-9, 13, and their oxetane ring opened derivatives 14, 16, and 17, which were synthesized from taxinine, showed significant activity as MDR reversal agent by the assay of the calcein accumulatio
Synthesis and antitumor activity of 2-(m-substituted-benzoyl)baccatin III analogs from taxinine
Horiguchi, Tohru,Oritani, Takayuki,Kiyota, Hiromasa
, p. 1529 - 1538 (2007/10/03)
2-m-Azidobenzoyl and 2-m-chlorobenzoyl baccatin III analogs were prepared from taxinine, a major component in Japanese yew leaves. In this study, a novel acetyl migration from 13- to 4-hydroxyl group was observed. The antitumor activity of these compounds
