5330-63-2

Basic information

• Product Name: ert-butyl N-(3-chlorophenyl)carbamate
• Synonyms: ert-butyl N-(3-chlorophenyl)carbamate;tert-butyl N-(3-chlorophenyl)carbamate
• CAS NO: 5330-63-2
• Molecular Formula: C₁₁H₁₄ClNO₂
• Molecular Weight: 227.68736
• Mol File: 5330-63-2.mol
• Article Data: 34

Chemical Properties

• Boiling Point: 263.8°C at 760 mmHg
• Flash Point: 113.4°C
• Appearance: /
• Density: 1.195g/cm³
• Vapor Pressure: 0.0101mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: ert-butyl N-(3-chlorophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ert-butyl N-(3-chlorophenyl)carbamate(5330-63-2)
• EPA Substance Registry System: ert-butyl N-(3-chlorophenyl)carbamate(5330-63-2)

Safety Data

• Hazardous Substances Data: 5330-63-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14ClNO2/c1-11(2,3)15-10(14)13-9-6-4-5-8(12)7-9/h4-7H,1-3H3,(H,13,14)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 108-42-9 3-chloro-aniline 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 4248-19-5 tert-butyl carbazate 
• 108-90-7 chlorobenzene 
• 110-05-4 di-tert-butyl peroxide 
• 32686-54-7 m-chlorophenyl isocyanide 
• 1239374-13-0 tert-butyl 3-chlorophenyl(3-perfluorooctylpropoxy)carbamate 

Downstream Products

• 652153-34-9 (3-chlorophenyl)-(4-chloro-[1,3,5]triazin-2-yl)carbamic acid tert-butyl ester 
• 3422-01-3 tert-butyl phenylcarbamate 
• 108-42-9 3-chloro-aniline 
• 18109-43-8 N-(3-chlorophenyl)-2-phenylacetamide 
• 7006-52-2 3-chloro-N-methylaniline 
• 39165-01-0 N-(3-chlorophenyl)-2-oxo-2-phenylacetamide 
• 1186637-28-4 N-(tert-butoxycarbonyl)-5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 1384312-60-0 N-(tert-butoxycarbonyl)-5-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 1384312-79-1 N-(tert-butoxycarbonyl)-N-methyl-3-chloroaniline 
• 1384313-14-7 C₁₇H₂₄⁽²⁾HBClNO₄ 
• 1384313-16-9 C₁₇H₂₄⁽²⁾HBClNO₄ 
• 1384313-08-9 N-(tert-butoxycarbonyl)-N-methyl-3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 652153-43-0 [4-(2-{tert-butoxycarbonyl-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-amino}-pyridin-4-yl)-[1,3,5]triazin-2-yl]-(3-chloro-phenyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Mild deprotection of the: N-tert -butyloxycarbonyl (N -Boc) group using oxalyl chloride

We report a mild method for the selective deprotection of the N-Boc group from a structurally diverse set of compounds, encompassing aliphatic, aromatic, and heterocyclic substrates by using oxalyl chloride in methanol. The reactions take place under room temperature conditions for 1-4 h with yields up to 90percent. This mild procedure was applied to a hybrid, medicinally active compound FC1, which is a novel dual inhibitor of IDO1 and DNA Pol gamma. A broader mechanism involving the electrophilic character of oxalyl chloride is postulated for this deprotection strategy. This journal is

PRODUCTION METHOD FOR AMIDATE COMPOUND

A method for producing an amidate compound represented by Formula (3), comprising reacting a urethane compound represented by Formula (1) with a carboxylate compound represented by Formula (2): (in the formulas, A, n, R1, R2, R3, R4, R5, R6, X, and a are as described in the Description).

Selective Oxidative Coupling Reaction of Isocyanides Using Peroxide as Switchable Alkylating and Alkoxylating Reagent

A switchable oxidative coupling reaction of isocyanide and peroxide has been disclosed. In the presence of iron catalyst, the coupling reaction affords N-arylacetamides in good yields. By simply replacing the iron with copper catalyst, another different coupling reaction takes place in which peroxide can serve as alkoxylating source. This protocol represents a new fundamental coupling of two basic chemicals involving C?C and C?O bond-forming process. The unusual reactivity of an isocyano group in a radical reaction acting formally as an amidoyl synthon has also been well established. The experiment outcome reveals that aromatic isocyanides are particularly compatible reaction partners in present coupling reaction, whereas no desired products are observed when aliphatic isocyanides are used. (Figure presented.).