5335-90-0

Usage

Uses

Used in Pharmaceutical Industry:
(2E)-1-(2-nitrophenyl)-2-(phenylmethylidene)hydrazine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the creation of complex organic molecules.
Used in Dye Industry:
In the dye industry, (2E)-1-(2-nitrophenyl)-2-(phenylmethylidene)hydrazine is used as a precursor in the production of dyes, contributing to the development of colorants for various applications.
Used in Organic Compounds Synthesis:
(2E)-1-(2-nitrophenyl)-2-(phenylmethylidene)hydrazine is used as a reagent in the synthesis of other organic compounds, playing a crucial role in the formation of desired products in chemical reactions.
Safety and Disposal:
It is important to handle (2E)-1-(2-nitrophenyl)-2-(phenylmethylidene)hydrazine with care, as it may be harmful if ingested, inhaled, or comes into contact with the skin. Additionally, due to potential environmental implications, it should be properly disposed of according to local regulations.

Upstream product

• 100541-73-9 ((Z)-2-nitro-phenylhydrazono)-phenyl-acetic acid 
• 100-52-7 benzaldehyde 
• 3034-19-3 (2-nitrophenyl)hydrazine 
• 69852-67-1 (2-nitro-phenylhydrazono)-phenyl-acetonitrile 
• 1296783-86-2 1,2'-diphenyl-3,5-dioxo-1,2,3,5-tetrahydrospiropyrazole-4,3'-oxirane 

Downstream Products

• 78818-70-9 1-o-Nitrophenyl-3,5-diphenylformazan 
• 4913-40-0 N'-(4-bromo-2-nitro-phenyl)-benzohydrazonoyl bromide 
• 716-79-0 2-phenyl-1H-benzoimidazole 
• 53314-15-1 benzaldehyde-(2-amino-phenylhydrazone) 
• 69918-15-6 Benzoylbromid-2-nitrophenylhydrazon 
• 24414-86-6 benzil-mono-(2-nitro-phenylhydrazone) 

Relevant academic research and scientific papers

Novel synthesis of highly functionalized pyrazolone systems via rearrangement of 5-phenyl-1-oxa-5,6-diazaspiro[2.4]heptane-4,7-diones

Epoxidation of 4-alkylidene(arylidene)-1-phenyl-3,5-pyrazolidinediones using alkaline hydrogen peroxide gave the corresponding 5-phenyl-1-oxa-5,6- diazaspiro[2.4]heptane-4,7-dione derivatives. Their reaction with nucleophilic reagents was investigated. The resulting products depend on the type of the diazaspiro compound and/or the nucleophile used.

Synthesis, spectral and structural studies, and an evaluation of the hydrogen bonding of some phenylhydrazones

A series of 46 phenylhydrazones, some novel, containing a variety of structural types has been synthesised. These have been studied by 1H n.m.r. and i.r. spectroscopy with respect to potential inter- and intra-molecular hydrogen bonding. ortho-Nitro or -carbonyl groups form strong hydrogen bonds to the imino-group which are readily observed by 1H n.m.r. but not by i.r. spectroscopy. 'Terminal' carbonyl groups also form strong hydrogen bonds to the imino-group and these can be detected by both i.r. and 1H n.m.r. spectroscopy. When both ortho-nitro- or -carbonyl groups and 'terminal' carbonyl groups are present the imino hydrogen atom is doubly hydrogen bonded and this is apparent in the 1H n.m.r. spectrum. The formation of an intramolecular hydrogen bond in the phenylhydrazone prevents the formation of an intermolecular hydrogen bond between the phenylhydrazone and a polar solvent.