5336-62-9

Usage

Type of Compound

Amine derivative

Structural Features

Methoxy group (-OCH3) attached to the phenyl ring
Methyl group (-CH3) attached to the phenyl ring
Two dimethylamine groups (-N(CH3)2) attached to the central carbon atom

Phenyl Ring

Contains a benzene ring with a methoxy and a methyl group as substituents

Functional Groups

Amine (-NH2), methoxy (-OCH3), and methyl (-CH3)

Usage

Reagent in organic synthesis
Pharmaceutical research (potential precursor to pharmaceutical compounds)
Production of dyes
Production of pesticides
Other organic compounds

Research Status

Properties and potential applications are still under investigation by researchers

Upstream product

• 17734-35-9 1-(4-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide 
• 15175-54-9 N,N-dimethyl-4-methoxylbenzylamine 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 126062-57-5 dimethyl(4-methoxybenzyl)<(trimethylsilyl)methyl>ammonium iodide 
• 108481-83-0 (4-methoxy-benzyl)-trimethyl-ammonium; bromide 

Downstream Products

• 3168-59-0 5-methoxy-o-toluic acid 
• 56724-09-5 5-methoxy-2-methylbenzaldehyde 
• 61582-77-2 4-Methoxy-1-methyl-2-phenethyl-benzene 
• 61582-78-3 4-Methoxy-2-[2-(2-methoxy-phenyl)-ethyl]-1-methyl-benzene 
• 61582-80-7 4-Methoxy-2-[2-(3-methoxy-phenyl)-ethyl]-1-methyl-benzene 
• 61582-79-4 2-Methyl-4',5-dimethoxydibenzyl 
• 73502-04-2 (5-methoxy-2-methylphenyl)methanol 
• 1885-13-8 4-methoxyphthalic acid 

Relevant academic research and scientific papers

Synthesis of N,N-dimethyl-2-(tributylstannyl)methyl-5-substituted benzylamines as a quinodimethane precursor by the reaction of N,N-dimethyl- N-(tributylstannyl)methyl-4-substituted benzylammonium salts with lithium diisopropylamide

Reaction of N,N-dimethyl-N-(tributylstannyl)methyl-4-substituted benzylammonium salts 2 with lithium diisopropylamide (LDA) gave N,N-dimethyl- 2-(tributylstannyl)methyl-5-substituted benzylamines 3 as the main products. Treatment of 3 with iodomethane followed by tetrabutylammonium fluoride (TBAF) in the presence of dimethyl fumarate gave the corresponding dimethyl trans-1,2,3,4-tetrahydro-6-substituted naphthalene-2,3-dicarboxylates 15 in good yields.

CYCLISATION DE DIARYLALCANES EN MILIEU SUPERACIDE: SYNTHESE DE CETONES TRICYCLIQUES A METHYLE ANGULAIRE ET MECANISME DE LEUR ISOMERISATION

Cyclisation of redily available diaryl-1,2 ethanes 1-4 proceeds in SbF5-HF at 0oC to yield tricyclic phenantrenones 5,6,7 and 11 bearing an angular methyl group.This process implies the electrophilic attack of the more basic aromatic ring, reacting through its disprotonated form (on the oxygen and the meta carbon atom) on the second aromatic ring.Isomerization of these primary products may be observed (to give ketones 8,9,10 from 3 and 12 from 4) and it has been demonstrated by the use of specifically deuterated 3d that it involves stereospecific 1,2 hydride (or deuteride) shifts, without exchange.