5338-16-9 Usage
Description
GUANYLUREA SULFATE, a white powder with a purity of greater than 97%, is a chemical compound known for its solubility in water and alcohol. It is a versatile substance with various applications across different industries due to its unique chemical properties.
Uses
Used in Analytical Chemistry:
GUANYLUREA SULFATE is used as an analytical reagent for the detection and measurement of nickel. Its chemical properties make it suitable for this application, allowing for accurate and reliable results in the analysis of nickel content in various samples.
Used in Dye Manufacturing:
In the dye industry, GUANYLUREA SULFATE serves as a crucial component in the manufacturing process of dyes. Its chemical structure contributes to the development of dyes with specific properties, such as color intensity and stability, making it an essential ingredient in the production of a wide range of dyes.
Used in Organic Synthesis:
GUANYLUREA SULFATE is also utilized in organic synthesis, where it acts as a key building block for the creation of various organic compounds. Its reactivity and solubility properties enable chemists to synthesize a diverse array of organic molecules, contributing to the development of new materials and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 5338-16-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,3 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5338-16:
(6*5)+(5*3)+(4*3)+(3*8)+(2*1)+(1*6)=89
89 % 10 = 9
So 5338-16-9 is a valid CAS Registry Number.
InChI:InChI=1/C2H6N4O.H2O4S/c3-1(4)6-2(5)7;1-5(2,3)4/h(H6,3,4,5,6,7);(H2,1,2,3,4)/p-1
5338-16-9Relevant articles and documents
Multitarget drug discovery for Alzheimer's disease: Triazinones as BACE-1 and GSK-3β inhibitors
Prati, Federica,De Simone, Angela,Bisignano, Paola,Armirotti, Andrea,Summa, Maria,Pizzirani, Daniela,Scarpelli, Rita,Perez, Daniel I.,Andrisano, Vincenza,Perez-Castillo, Ana,Monti, Barbara,Massenzio, Francesca,Polito, Letizia,Racchi, Marco,Favia, Angelo D.,Bottegoni, Giovanni,Martinez, Ana,Bolognesi, Maria Laura,Cavalli, Andrea
supporting information, p. 1578 - 1582 (2015/01/30)
Cumulative evidence strongly supports that the amyloid and tau hypotheses are not mutually exclusive, but concomitantly contribute to neurodegeneration in Alzheimer's disease (AD). Thus, the development of multitarget drugs which are involved in both pathways might represent a promising therapeutic strategy. Accordingly, reported here in is the discovery of 6-amino-4-phenyl-3, 4-dihydro-1, 3, 5-triazin-2(1H)-ones as the first class of molecules able to simultaneously modulate BACE-1 and GSK-3β. Notably, one triazinone showed well-balanced in vitro potencies against the two enzymes (IC50 of (18.03 ±0.01) μM and (14.67±0.78)μUM for BACE-1 and GSK-3β, respectively). In cell-based assays, it displayed effective neuroprotective and neurogenic activities and no neurotoxicity. It also showed good brain permeability in a preliminary pharmacokinetic assessment in mice. Overall, triazinones might represent a promising starting point towards high quality lead compounds with an AD-modifying potential.