53392-03-3

Basic information

• Product Name: Silane, triethoxy(3-methoxyphenyl)-
• CAS NO: 53392-03-3
• Molecular Formula: C13H22O4Si
• Molecular Weight: 270.401
• Mol File: 53392-03-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Silane, triethoxy(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, triethoxy(3-methoxyphenyl)-(53392-03-3)
• EPA Substance Registry System: Silane, triethoxy(3-methoxyphenyl)-(53392-03-3)

Safety Data

• Hazardous Substances Data: 53392-03-3(Hazardous Substances Data)

Upstream product

• 998-30-1 Triethoxysilane 
• 766-85-8 3-methoxy-1-iodobenzene 
• 78-10-4 tetraethoxy orthosilicate 
• 2398-37-0 3-methoxyphenyl bromide 

Downstream Products

• 27124-71-6 3-(3-methoxyphenyl)cyclohexene 
• 1527-89-5 3-methoxybenzonitrile 
• 1582806-69-6 (S)-3-(3-methoxyphenyl)-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide 
• 109251-14-1 2-methoxy-6-(3-methoxyphenyl)naphthalene 
• 32040-09-8 4-(3-methoxyphenyl)morpholine 
• 65442-22-0 (3-methoxyphenyl)phosphonic acid diethyl ester 
• 130754-15-3 ethyl 2-fluoro-2-(3-methoxyphenyl)acetate 
• 792-74-5 4,4'-biphenyldicarboxylic acid dimethyl ester 
• 81443-43-8 methyl 3'-Methoxy(1,1'-biphenyl)-4-carboxylate 
• 155061-61-3 3'-methoxy-biphenyl-4-carboxylic acid ethyl ester 
• 128460-75-3 methyl 3′-methoxy(1,1′-biphenyl)-3-carboxylate 
• 17595-93-6 2-(3-methoxyphenyl)thiophene 
• 4373-67-5 3-(3-methoxyphenyl)pyridine 
• 2113-56-6 3-methoxybiphenyl 

Relevant articles and documents

Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes

The stereoselective β-C(sp2)-H arylation of various acyclic enamides with arylsilanes via Rh(III)-catalyzed cross-coupling reaction was illustrated. The methodology was characterized by extraordinary efficacy and stereoselectivity, a wide scope of substrates, good functional group tolerance, and the adoption of environmentally friendly arylsilanes. The utility of this present method was evidenced by the gram-scale synthesis and further elaboration of the product. In addition, Rh(III)-catalyzed C-H activation is considered to be the critical step in the reaction mechanism.

Improved synthesis of aryltriethoxysilanes via palladium(O)-catalyzed silylation of aryl iodides and bromides with triethoxysilane

The scope of the palladium-catalyzed silylation of aryl halides with triethoxysilane has been expanded to include aryl bromides. A more general Pd(0) catalyst/ligand system has been developed that activates bromides and iodides: palladium(O) dibenzylideneacetone (Pd(dba)2) is activated with 2-(di-tert-butylphosphino)biphenyl (Buchwald's ligand) (1:2 mol ratio of Pd/phosphine). Electronrich para- and meta-substituted aryl halides (including unprotected aniline and phenol derivatives) undergo silylation to form the corresponding aryltriethoxysilane in fair to excellent yield; however, ortho-substituted aryl halides failed to be silylated.