5340-64-7

Basic information

• Product Name: 2,2-DIMETHYL-3-OCTANONE
• Synonyms: 2,2-DIMETHYL-3-OCTANONE;2,2-dimethyloctan-3-one
• CAS NO: 5340-64-7
• Molecular Formula: C₁₀H₂₀O
• Molecular Weight: 156.27
• Mol File: 5340-64-7.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 190.3°Cat760mmHg
• Flash Point: 54.3°C
• Appearance: /
• Density: 0.819g/cm³
• Vapor Pressure: 0.544mmHg at 25°C
• Refractive Index: 1.42
• CAS DataBase Reference: 2,2-DIMETHYL-3-OCTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-3-OCTANONE(5340-64-7)
• EPA Substance Registry System: 2,2-DIMETHYL-3-OCTANONE(5340-64-7)

Safety Data

• Hazardous Substances Data: 5340-64-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 17, p. 3155, 1976 DOI: 10.1016/S0040-4039(00)93866-8

InChI:InChI=1/C10H20O/c1-5-6-7-8-9(11)10(2,3)4/h5-8H2,1-4H3

Upstream product

• 64-17-5 ethanol 
• 859772-12-6 3-butyl-5,5-dimethyl-hexane-2,4-dione 
• 754-10-9 2,2-dimethylpropionamide 
• 693-25-4 n-pentylmagnesium bromide 
• 628-73-9 hexanenitrile 
• 507-20-0 tertiary butyl chloride 
• 106-70-7 methyl hexanoate 
• 594-19-4 tert.-butyl lithium 
• 23532-74-3 9-butyl-9-borabicyclo<3.3.1>nonane 
• 5469-26-1 1-Bromopinacolon 
• 19841-72-6 2,2-dimethoxy-3-octanol 
• 677-22-5 tert-butylmagnesium chloride 
• 142-62-1 hexanoic acid 
• 109-67-1 1-penten 

Downstream Products

• 87280-51-1 (4SR,5RS)-4-butyl-2,2-dimethyl-5-phenyl-5-(trimethylsilyl)oxy-3-pentanone 
• 87280-48-6 (4SR,5SR)-4-butyl-2,2-dimethyl-5-phenyl-5-(trimethylsilyl)oxy-3-pentanone 

Relevant articles and documents

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An alkoxyamine compound, alkoxy alcohol oxidation catalyst and method of using the alcohol oxidation

PROBLEM TO BE SOLVED: To provide a novel alkoxyamine compound which can be easily manufactured and applied suitably as an alcohol oxidation catalyst capable of exerting sufficiently high catalytic activity in oxidation of primary and secondary alcohols.SOLUTION: There is provided an alkoxyamine compound with a homoadamantane skeleton represented by the general formula (1) in the figure. [In the formula (1), Rand Rare each independently any one selected from the group consisting of a hydrogen atom and alkyl groups that may be substituted.

Mechanistic insight into aerobic alcohol oxidation using NOx-nitroxide catalysis based on catalyst structure-activity relationships

The mechanism of an NOx-assisted, nitroxide(nitroxyl radical)-catalyzed aerobic oxidation of alcohols was investigated using a set of sterically and electronically modified nitroxides (i.e., TEMPO, AZADO (1), 5-F-AZADO (2), 5,7-DiF-AZADO (3), 5-MeO-AZADO (4), 5,7-DiMeO-AZADO (5), oxa-AZADO (6), TsN-AZADO (7), and DiAZADO (8)). The motivation for the present study stemmed from our previous observation that the introduction of an F atom at a remote position from the nitroxyl radical moiety on the azaadamantane nucleus effectively enhanced the catalytic activity under typical NOx-mediated aerobic-oxidation conditions. The kinetic profiles of the azaadamantane-N-oxyl-[AZADO (1)-, 5-F-AZADO (2)-, and 5,7-DiF-AZADO (3)]-catalyzed aerobic oxidations were closely investigated, revealing that AZADO (1) showed a high initial reaction rate compared to 5-F-AZADO (2) and 5,7-DiF-AZADO (3); however, AZADO-catalyzed oxidation exhibited a marked slowdown, resulting in ～90% conversion, whereas 5-F-AZADO-catalyzed oxidation smoothly reached completion without a marked slowdown. The reasons for the marked slowdown and the role of the fluoro group are discussed. Oxa-AZADO (6), TsN-AZADO (7), and DiAZADO (8) were designed and synthesized to confirm their comparable catalytic efficiency to that of 5-F-AZADO (2), providing supporting evidence for the electronic effect on the catalytic efficiency of the heteroatoms under NOx-assisted aerobic-oxidation conditions.