53405-05-3Relevant articles and documents
CuICuIIand AgI: P -isocyanobenzoates as novel 1D semiconducting coordination oligomers
Cano, Arely,Ramírez-Rosales, Daniel,Reguera, Edilso,Reguera, Leslie,Rivera, Daniel G.,Rodríguez-Hernández, Joelis,Van Der Eycken, Erik V.
, p. 12432 - 12440 (2020/10/02)
Two novel semiconducting coordination oligomers with 1D chain structures, namely [H0.07 CuI0.65CuII0.14(μ-p-CNC6H4CO2)·0.9H2O]n and [Ag(μ-p-CNC6H4CO2)]n, were obtained and characterized by XRD powder patterns, and XPS, EPR, UV-vis-NIR, IR and Raman spectroscopy. According to XRD analysis, CuICuII-ICNBA is an amorphous solid, while AgI-ICNBA crystalizes with a monoclinic unit cell in the C2/c space group (Z = 4). The composition and further information of CuICuII-ICNBA were obtained from the spectroscopic data. In correspondence with the quantification of terminal groups from high-resolution XPS spectra, CuICuII-ICNBA and AgI-ICNBA are composed of an average of 9 and 7 monomer units, respectively, resulting in 1D-oligomers. The spectroscopic evidence indicates that CuICuII-ICNBA is better described as a non-stoichiometric coordination oligomer (where non-integer ratios of metal ions can be accommodated), while AgI-ICNBA is stoichiometric. In both materials, each metal center is linked by two μ-η1:η1-p-isocyanobenzoate ligands forming microfibers of around 120 nm (CuICuII-material) and 310 nm (AgI-material) in average diameters with optical band gaps of 2.60 eV and 2.17 eV, respectively.
A more sustainable and highly practicable synthesis of aliphatic isocyanides
Waibel,Nickisch,M?hl,Seim,Meier
, p. 933 - 941 (2020/02/21)
Synthesis protocols to convert N-formamides into isocyanides using three different dehydration reagents (i.e. p-toluenesulfonyl chloride (p-TsCl), phosphoryl trichloride (POCl3) and the combination of triphenylphosphane (PPh3) and iodine) were investigated and optimized, while considering the principles of green chemistry. Comparison of the yield and the E-factors of the different synthesis procedures revealed that, in contrast to the typically applied POCl3 or phosgene derivatives, p-TsCl was the reagent of choice for non sterically demanding aliphatic mono- or di-N-formamides (yields up to 98% and lowest E-factor 6.45). Apart from a significantly reduced E-factor, p-TsCl is cheap, offers a simplified reaction protocol and work-up, and is less toxic compared to other dehydration reagents. Thus, this procedure offers easier and greener access to aliphatic isocyanide functionalities.
Synthesis of reversed C-glycopeptide mimics monomer from galactose via passerini reaction
Jalib, Muhammad Atif,Nabeel, Muhammad,Ali, Firdous Imran,Bari, Ahmed,Musharraf, Syed Ghulam,Hashmi, Imran Ali
, p. 792 - 798 (2018/07/15)
C-glycopeptidomimetics are formed by the condensation of sugar unit and analogues of amino acid residue which generates a new carbon-carbon sigma bond. In glycopeptides, this condensation occurs in side chain of amino acid but introduction of isonitrile moiety on N-terminal of amino acid mimic unit can also be a route to produce such compounds. It is observed that C-glycopeptidomimetics are more stable than their N- and O-analogues under physiological conditions but their synthesis is a challenging task due to relatively less reactive C-6 position of hexose. In present work, synthesis of reversed C-glycopeptidomimetics (pseudoglycopeptides) was done by Passerini reaction protocol which is famous for peptide synthesis due to its mild conditions and easy workup. This paper discusses the use of α-D-galactose, a cheap and easily available monosaccharide to prepare reversed C-glycopeptidomimetics. The term reversed C-glycopeptidomimetics is derived for its analogy with reversed C-nucleosides, as in these reactions, instead of anomeric carbon i.e. more reactive site, C-6 undergoes to produce desired products.
