534572-67-3

Usage

Chemical Properties

Yellow Solid

Upstream product

• 100-39-0 benzyl bromide 
• 162784-26-1 17,17-ethylenedioxy-3-benzyloxy-estra-1,3,5 ⁽¹⁰⁾-trien-17-one 
• 858-98-0 3-benzyloxyestra-1,3,5⁽¹⁰⁾-trien-17-one 
• 690996-27-1 16-bromo-17,17-ethylenedioxy-3-benzyloxy-estra-1,3,5 ⁽¹⁰⁾-trien-17-one 

Downstream Products

• 138743-03-0 (14α)-3-benzyloxy-1,3,5(10),15-estratetraen-17-one 
• 138743-04-1 3-benzyloxy-15(α,β)-<9'-<(tetrahydro-2''H-pyran-2''-yl)oxy>-1'-nonanyl>-1,3,5(10)-estratriene-17-one 
• 138743-08-5 N-butyl, N-methyl-9-(3'-benzyloxy-17'-oxo-1',3',5'(10')-estratriene-15'(α,β)-yl)-nonamide 
• 138743-09-6 N-butyl, N-methyl-9-(3'-benzyloxy-17'β-hydroxy-1',3',5'(10')-estratriene-15'(α,β)-yl)-nonamide 
• 138743-06-3 3-benzyloxy-15(α,β)-(9'-hydroxy-1'-nonanyl)-1,3,5(10)-estratriene-17-one 
• 534572-83-3 diethyl (3-benzyloxy-17-oxoestra-1,3,5(10)-trien-15α-yl)malonate 
• 534572-96-8 3-(17β-acetoxy-3-benzyloxyestra-1,3,5(10)-trien-15α-yl)propanoic acid 
• 534572-81-1 3-methoxy-17β-methoxymethoxy-15α-toluenesulfonyloxymethylestra-1,3,5(10)-triene 
• 534572-95-7 (3-benzyloxy-15α-(3'-hydroxypropyl)estra-1,3,5(10)-trien-17β-yl) acetate 
• 534572-94-6 (15α-allyl-3-benzyloxyestra-1,3,5(10)-trien-17β-yl) acetate 
• 534572-97-9 3-(3-benzyloxy-17β-hydroxyestra-1,3,5(10)-trien-15α-yl)propanoic acid 
• 534572-70-8 (15α,17β)-3-(benzyloxy)-17-hydroxyestra-1,3,5(10)-triene-15-carboxylic acid 
• 534572-93-5 15α-allyl-3-benzyloxyestra-1,3,5(10)-trien-17β-ol 
• 534572-92-4 15α-allyl-3-benzyloxyestra-1,3,5(10)-trien-17-one 

Relevant academic research and scientific papers

SYNTHESIS OF ESTETROL VIA ESTRONE DERIVED STEROIDS

A process is provided for the making of estetrol starting from a 3-A-oxy-estra 1,3,5(10),15-tetraen-17-one, wherein A is an C1-C5 alkyl group, preferably a methyl group, or a C7 - C12 benzylic group, preferably a benzyl group. This process is particularly suitable to industry.

15Alpha-substituted estradiol carboxylic acid esters as locally active estrogens

The present invention relates to analogs of estradiol, which, in their most preferred embodiment, act as locally active estrogens without significant systemic action. A series of 15α-estradiol ester compounds is presented which exhibit excellent biologica

Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens

We have synthesized derivatives of estradiol that are structurally modified to serve as "soft" estrogens and act within a geographically limited area of the body; estrogens without systemic action. We have previously shown with 16α-substituted analogues o

SYNTHESIS OF 17β-ESTRADIOL DERIVATIVES WITH N-BUTYL, N-METHYL ALKYLAMIDE SIDE CHAIN AT POSITION 15

New derivatives of 17-β-estradiol with N-butyl, N-methyl alkylamide side chains of three different lengths at position 15 have been synthesized from estrone.Compounds 5 and 6 having a shorter alkylamide chain were obtained in eleven steps by introduction