53484-13-2

Basic information

• Product Name: 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI)
• Synonyms: 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI);1-Methyl-1H-benzo[d]imidazole-5-carbonitrile;5-Cyano-1-methylbenzoimidazole;1-methyl-1H-benzimidazole-5-carbonitrile(SALTDATA: FREE)
• CAS NO: 53484-13-2
• Molecular Formula: C9H7N3
• Molecular Weight: 157.17198
• Product Categories: BENZIMIDAZOLE
• Mol File: 53484-13-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI)(53484-13-2)
• EPA Substance Registry System: 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI)(53484-13-2)

Safety Data

• Hazardous Substances Data: 53484-13-2(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI) is a chemical compound with the molecular formula C9H7N3. It is a derivative of benzimidazole, a heterocyclic compound containing a fused benzene and imidazole ring system. 1H-Benzimidazole-5-carbonitrile,1-methyl-(9CI) is a nitrile, which means it contains a carbon triple-bonded to a nitrogen atom. The presence of a methyl group on the benzimidazole ring distinguishes it as 1-methyl-1H-benzimidazole-5-carbonitrile. This chemical may have potential applications in pharmaceuticals, as benzimidazole derivatives have been found to exhibit various biological activities, including anti-cancer, anti-inflammatory, and anti-fungal properties. Further research and testing may reveal its specific uses and potential benefits in various industries.

Upstream product

• 67-56-1 methanol 
• 64910-46-9 3-amino-4-(methylamino)benzonitrile 
• 64910-45-8 4-(methylamino)-3-nitrobenzonitrile 
• 939-80-0 4-chloro-3-nitrobenzonitrile 

Relevant articles and documents

Using Methanol as a Formaldehyde Surrogate for Sustainable Synthesis of N-Heterocycles via Manganese-Catalyzed Dehydrogenative Cyclization

The development of an efficient and sustainable synthetic route for formaldehyde production from renewable feedstock, especially in combination with a subsequent transformation to straightforwardly construct valuable chemicals, is highly desirable. Herein, we report a novel manganese-catalyzed dehydrogenative cyclization of methanol as a formaldehyde surrogate with a variety of dinucleophiles for facile synthesis of N-heterocycles. The in situ generated formaldehyde via catalytic methanol dehydrogenation can be selectively trapped by diverse dinucleophiles to avoid several possible side reactions. The utility of this transformation is further highlighted by its successful application to the synthesis of 13C-labeled N-heterocycles using 13CH3OH as a readily accessible 13C-isotope reagent.

2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS

The present invention provides compounds that are useful as vaccine adjuvants and/or antitumor agents and methods for producing and using the same. In one particular aspect of the invention, compounds of the invention are of the formula (I) where R1, R2, R3 and Ar1 are those defined herein.