53484-17-6

Basic information

• Product Name: 1-Methyl-1H-benzimidazole-5-carboxylic acid
• Synonyms: 1-methyl-1H-benzo[d]imidazole-5-carboxylic acid;1-Methyl-1H-1,3-benzimidazole-5-carboxylic acid;1-Methylbenzodiazole-5-carboxylic acid;5-Carboxy-1-methyl-1H-benzimidazole;1-Methyl-1H-benzimidazole-5-carboxylicacid97%;1-methyl-1H-benzo[d]imidazol-5-carboxylic acid;1-Methyl-1H-benzimidazole-5-carboxylic acid 97%;1H-Benzimidazole-5-carboxylicacid,1-methyl-(9CI)
• CAS NO: 53484-17-6
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.18
• Product Categories: BENZIMIDAZOLE
• Mol File: 53484-17-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: >300(dec.)
• Boiling Point: 411.1°Cat760mmHg
• Flash Point: 202.4°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 1.7E-07mmHg at 25°C
• Refractive Index: 1.653
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.92±0.30(Predicted)
• CAS DataBase Reference: 1-Methyl-1H-benzimidazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-1H-benzimidazole-5-carboxylic acid(53484-17-6)
• EPA Substance Registry System: 1-Methyl-1H-benzimidazole-5-carboxylic acid(53484-17-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 53484-17-6(Hazardous Substances Data)

Usage

General Description

1-Methyl-1H-benzimidazole-5-carboxylic acid is an organic chemical compound having the molecular formula C10H9N2O2. It falls under the class of benzimidazoles, which is characterized by a benzene ring fused to an imidazole ring. This chemical is used in a variety of applications, particularly in the field of synthetic chemistry where it can be utilized as a building block for drug design and discovery. Whether in academic research or industrial settings, this chemical plays a crucial role in facilitating advancements in scientific understanding and creating novel compounds with potential therapeutic applications.

InChI:InChI=1/C9H8N2O2/c1-11-5-10-7-4-6(9(12)13)2-3-8(7)11/h2-5H,1H3,(H,12,13)

Upstream product

• 53484-19-8 ethyl 1-methyl-1H-benzo[d]imidazole-5-carboxylate 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 41263-74-5 4-(methylamino)-3-nitrobenzoic acid 
• 66315-23-9 ethyl 3-amino-4-(methylamino)benzoate 
• 64-18-6 formic acid 
• 66315-15-9 3-amino-4-(methylamino)benzoic acid 
• 131020-36-5 methyl 1-methyl-1H-benzo[d]imidazole-5-carboxylate 

Downstream Products

• 916587-20-7 C₁₇H₁₉N₃ 
• 265107-91-3 1-(1-methyl-1H-benzo[d]imidazol-5-yl)ethan-1-one 
• 916587-19-4 C₁₇H₁₇N₃O 
• 131020-36-5 methyl 1-methyl-1H-benzo[d]imidazole-5-carboxylate 

Relevant articles and documents

NOVEL ARYLALKENE DERIVATIVES AND USE THEREOF AS SELECTIVE ESTROGEN RECEPTOR MODULATORS

The invention provides novel ethylene derivatives represented by Formula I, which may be used as selective estrogen receptor modulators (SERMs) and useful in the prophylaxis and/or treatment of estrogen-dependent conditions or conditions.

INHIBITORS OF HISTONE DEACETYLASE

The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

HETEROCYCLICALLY SUBSTITUTED INDOLINONES, THEIR PRODUCTION AND USE AS MEDICAMENTS

The invention relates to heterocyclically substituted indolinones of general formula (I), in which R1 to R5 and X are defined as cited in claim 1, to their tautomers, diastereomers, enantiomers and to their mixtures, prodrugs and salts, in particular their physiologically compatible salts. Said compounds exhibit valuable pharmacological characteristics, in particular an inhibiting action on various receptor tyrosine kinases and cyclin-CDK complexes and on the proliferation of endothelial cells and various tumour cells. The invention also relates to medicaments containing said compounds, to the use of the latter and to a method for producing the same.