53502-60-6

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
1-(2-chloroethyl)piperazine is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the development of bioactive molecules with potential therapeutic and pesticidal properties.
Used in Drug Delivery Systems:
1-(2-chloroethyl)piperazine is utilized as a drug delivery agent to enhance the efficacy and targeted delivery of pharmaceutical compounds, potentially improving their bioavailability and therapeutic outcomes.
Used in the Development of New Bioactive Compounds:
As a building block, 1-(2-chloroethyl)piperazine is employed in the creation of novel bioactive compounds, leveraging its chemical structure to explore new avenues in medicinal chemistry and drug discovery.
Used in Environmental and Health Risk Assessment:
Given its organochlorine nature, 1-(2-chloroethyl)piperazine is also used in studies and assessments related to environmental and health risks, ensuring that its applications are conducted with proper safety measures and disposal protocols.

InChI:InChI=1/C6H13ClN2/c7-1-4-9-5-2-8-3-6-9/h8H,1-6H2

Upstream product

• 5712-71-0 1-(2-hydroxyethyl)piperazine dihydrochloride 
• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 110-85-0 piperazine 
• 107-15-3 ethylenediamine 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 280-57-9 1,4-diaza-bicyclo[2.2.2]octane 
• 19479-83-5 1,2-bis(piperazinyl)-ethane 
• 314725-99-0 4,6-Diamino-5-(2-methoxybenzyl)-2-[2-(1-piperazinyl)ethylthio]-pyrimidine fumarate 
• 137554-12-2 Ethyl-(2-piperazin-1-yl-ethyl)-amine 
• 314726-23-3 4,6-Diamino-2-[2-(1-piperazinyl)ethylthio]-5-(4-isopropylbenzyl)-pyrimidine 
• 314725-98-9 4,6-Diamino-5-(2-methoxybenzyl)-2-[2-(1-piperazinyl)ethylthio]-pyrimidine 
• 314726-14-2 4,6-Diamino-2-[2-(4-acetyl-1-piperazinyl)ethylthio]-5-(2-methoxybenzyl)pyrimidine 
• 24028-46-4 1-<2-(2-aminoethyl)aminoethyl>piperazine 

Relevant academic research and scientific papers

Amine ethylated piperazine and preparation method thereof

The invention provides a preparation method of an amine ethylated piperazine, and relates to the technical field of preparation of aminoethyl piperazine. The method comprises the following steps: mixing a piperazine compound, a chlorination reagent and a soluble piperazine compound solvent to carry out chlorination reaction to obtain the chloropiperazine hydrochloride. The piperazine compound comprises 2 - hydroxyethyl piperazine or N, N' - bis (2 - hydroxyethyl) piperazine. The chloropiperazine hydrochloride, the organic amine and the water are mixed, and the substitution reaction is carried out to obtain the aminated piperazine. The organic amine includes methylamine. Diethylamine, propylamine. The preparation method provided by the invention is high in product yield, high in purity, simple to operate, wide in reaction raw material source, low in production cost and suitable for industrial production.

Cationic polysaccharides and reagents for their preparation

Cationic polysaccharide derivatives are prepared by reacting a polysaccharide with a polycationic reagent having one polysaccharide reactive group and at least two cationic groups. Suitable reagents include polycationic alkyl, aryl, alkaryl, cycloaliphatic, or heterocyclic amines, some of which are novel compositions. The polycationic polysaccharide derivatives prepared from these reagents are useful in the manufacture of paper.