53576-52-6Relevant academic research and scientific papers
Formation of diverse mesophases templated by a diprotic anionic surfactant
Gao, Chuanbo,Sakamoto, Yasuhiro,Terasaki, Osamu,Che, Shunai
, p. 11423 - 11428 (2008)
The synthesis system for mesophase formation, using the diprotic anionic surfactant N-myristoyl-L-glutamic acid (C14GluA) as the structure-directing agent (SDA) and N-trimethoxylsilylpropyl-N,N,N-trimethyl- ammonium chloride (TMAPS) as the co-structure-directing agent (CSDA), has been investigated and a full-scaled synthesis-field diagram is presented. In this system we have obtained mesophases including three-dimensional (3D) micellar cubic Fm3m, Pm3n, Fd3m, micellar tetragonal P4 2/mnm, two-dimensional (2D) hexagonal p6mm and bicontinuous cubic Pn3m, by varying the C14GluA/NaOH/TMAPS composition ratios. From the diagram it can be concluded that the mesophase formation is affected to a high degree by the organic/inorganic-interface curvature and the mesocage-mesocage electrostatic interaction. Bi-continuous cubic and 2D-hexagonal phases were found in the low organic/inorganic-interface curvature zones, whereas micellar cubic and tetragonal mesophases were found in the high organic/inorganic-interface curvature zones. Formation of cubic Fm3m and tetragonal PA2/mnm was favoured in highly alkaline zones with strong mesocage-mesocage interactions, and formation of cubic Pm3n and Fd3m was favoured with moderate mesocage-mesocage interactions in the less alkaline zones of the diagram.
Synthesis and characterization of mesoporous silica AMS-10 with bicontinuous cubic Pn3m symmetry
Gao, Chuanbo,Sakamoto, Yasuhiro,Sakamoto, Kazutami,Terasaki, Osamu,Che, Shunai
, p. 4295 - 4298 (2006)
(Figure Presented) Woven into place: By precisely controlling the neutralization degree of the anionic surfactant template, mesoporous silica with different structures was prepared, such as AMS-10. Detailed characterizations of AMS-10 show that it is a novel bicontinuous cubic Pn3m mesophase. The mesostructure is composed of an interwoven enantiomeric pair of 3D networks (see picture).
pH-sensitive wormlike micelle and hydrogel formation by acylglutamic acid-alkylamine complex
Sakai, Kenichi,Sawa, Masahide,Nomura, Kazuyuki,Endo, Takeshi,Tsuchiya, Koji,Sakamoto, Kazutami,Abe, Masahiko,Sakai, Hideki
, p. 655 - 657 (2016/07/06)
pH-sensitive viscoelastic fluids were obtained through the formation of wormlike micelles and hydrogels. These assemblies result from the 1:1 stoichiometric complex formation of acylglutamic acid (CnGlu) with tertiary alkylamine. The pH-sensitive nature reflects a change in the charge density around the CnGlu headgroups, controlling the curvature of the molecular assemblies. The longer chainCnGlu analogues yield the hydrogel in a narrow pH region. This study proposes a unique way to obtain stimulus-responsive viscoelastic fluids by means of gemini-like amphiphiles.
N-Myristoylglutamic acid derivative of 3′-fluoro-3′- deoxythymidine as an organogel
Chhikara, Bhupender S.,Tiwari, Rakesh,Parang, Keykavous
supporting information, p. 5335 - 5337 (2012/11/07)
Designing microbicidal gels of anti-HIV drugs for local application to prevent HIV infection is a subject of major interest. 3′-Fluoro-3′- deoxythymidine (FLT), a nucleoside reverse transcriptase inhibitor (NRTI), was conjugated with a N-myristoylglutamate scaffold. The conjugate showed gelation at 1% (w/w) in different organic solvents, such as toluene, dichloromethane, and chloroform. The gels were opaque and stable at room temperature. The results indicate that myristoyl glutamate derivative of FLT can form an organogel. The gel could have potential application as a topical anti-HIV microbicidal agent.
Regulation of the chiral twist and supramolecular chirality in co-assemblies of amphiphilic L-glutamic acid with bipyridines
Zhu, Xuefeng,Duan, Pengfei,Zhang, Li,Liu, Minghua
, p. 3429 - 3437 (2011/05/02)
A series of amphiphilic L-glutamic acid derivatives with various saturated alkyl chains has been designed and their co-assembly with 4,4′-bipyridine in aqueous media has been investigated. While the individual amphiphiles formed hydrogels with water and self-assembled into fine fiber networks, the addition of 4,4′-bipyridine caused significant changes in the co-assembled nanostructures such that twisted chiral ribbons were formed. In these supramolecular systems, either fine structural changes or adjustment of the stoichiometric ratio of the two components had crucial effects on the formation of the chiral twists. Based on detailed investigations by SEM and XRD analyses, FTIR, CD, and UV/Vis spectroscopies, and molecular simulation, it is considered that a delicate synergistic balance between π-π stacking, hydrophobic, and chiral interactions is responsible for the formation of the chiral twists. An interesting sandwich structure, in which an excess of 4,4′-bipyridine is inserted into the space of primary cages constructed from the amphiphile and 4,4′-bipyridine, is proposed. Remarkably, the handedness of these chiral twists is related not only to the chiral center of the glutamic unit, but also the chain length of the alkyl tails. This work provides a deeper understanding of the formation mechanism of chiral twists, and exemplifies a feasible shortcut to the rational design of chiral structures from basic molecular structures to supramolecular systems. Twisted nanostructures: A chiral twist has been obtained through the co-assembly of single-chain L-glutamic acids with bipyridines (see picture). The sandwiching of additional 4,4′-bipyridine within the cage formed by the amphiphile and the bipyridine caused the chiral twist. The dimensions and chirality of the twist could be regulated by adjusting the alkyl chain length of the amphiphile. Copyright
