53651-61-9

Upstream product

• 700-13-0 Trimethylhydroquinone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 51857-41-1 4-bromo-2,3,6-trimethylphenol 
• 124-41-4 sodium methylate 
• 64-17-5 ethanol 
• 120-80-9 benzene-1,2-diol 
• 90-05-1 2-methoxy-phenol 
• 67-56-1 methanol 
• 130422-85-4 1-ethylenedioxy-2,3,5-trimethyl-2,5-cyclohexadien-4-ol 

Downstream Products

• 41145-19-1 3-chloromethyl-4-methoxy-2,5,6-trimethyl-phenol 
• 935-92-2 2,3,5-Trimethyl-1,4-benzoquinone 
• 858783-04-7 (3-hydroxy-6-methoxy-2,4,5-trimethyl-benzyl)-acetoacetic acid 
• 100863-90-9 4-(3-hydroxy-6-methoxy-2,4,5-trimethyl-phenyl)-butan-2-one 

Relevant academic research and scientific papers

A highly efficient approach to vanillin starting from 4-cresol

A highly efficient approach to the famous flavor and fragrance compound vanillin has been developed starting from 4-cresol with the attention focused on improving the sustainability of all the reactions. The approach involves a three-step sequence of the quasi-quantitative selective clean oxybromination of 4-cresol, the high-yield selective aerobic oxidation of 2-bromo-4-cresol, and the quantitative methoxylation of 3-bromo-4-hydroxybenzaldehyde with the recovery of pure methanol. Herein, the pivotal oxidation and methoxylation reactions are logically investigated and developed into two concise methodologies. As a green alternative, the approach holds significant value for the sustainable manufacturing of vanillin. the Partner Organisations 2014.

Transetherification of guaiacol to o-ethoxyphenol with gamma Al 2O3 as a catalyst in supercritical ethanol

The production of chemicals from lignin and lignin depolymerisation products is a promising alternative route to replace fossil fuels. Transetherification of guaiacol, a lignin derived model compound, to o-ethoxyphenol with γ-Al2O3 as the catalyst in supercritical ethanol has been investigated. The best reaction condition is 280°C for 3 h, giving a yield of 42% with a selectivity of 86%. A reaction pathway is also proposed. Besides, this work provides an example for producing a longer chain ether from a short chain ether.

SYNTHESIS OF DIQUINONE DERIVATIVES OF DEUTEROPORPHYRIN IX FOR THE STUDY OF THE FIRST STAGE IN THE PROCESS OF PHOTOSYNTHESIS

Diquinone derivatives of deuteroporphyrin IX containing covalent bridges of different lengths between the chromophores have been synthesized.The compounds were prepared by the condensation of hydroxy-quinones with deuteroporphyrin IX using a mixed anhydri

REGIOSELECTIVE SYNTHESIS OF 2,3,5-TRIMETHYL-p-BENZOQUINONE MONOACETAL AND ITS TRANSFORMATIONS

The addition of ethylene glycol to 2,3,5-trimethylbenzoquinone takes place regioselectively at the less screened carbonyl at position 1. 2,3,5-Trimethyl-p-benzoquinone ethylene 1-acetal is formed.The ethylene acetal protection is removed by acid hydrolysis.The use of ethylene acetal protection opened up a path to quinols containing aliphatic radicals at the carbonyl carbon.