53656-81-8

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
N-CYCLOHEXYL-N'-PHENYL-HYDRAZINE is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Polymer and Dye Production:
N-CYCLOHEXYL-N'-PHENYL-HYDRAZINE serves as a crucial building block in the production of different types of polymers and dyes, enhancing their properties and expanding their applications.
Used as a Corrosion Inhibitor:
N-CYCLOHEXYL-N'-PHENYL-HYDRAZINE has been studied for its potential as a corrosion inhibitor, offering protection to materials in various industries where corrosion is a concern.
Used as a Reagent in Organic Chemical Reactions:
In the field of organic chemistry, N-CYCLOHEXYL-N'-PHENYL-HYDRAZINE is utilized as a reagent, facilitating specific chemical reactions and contributing to the synthesis of complex organic molecules.
Used in Chemical Research:
Due to its unique structure and properties, N-CYCLOHEXYL-N'-PHENYL-HYDRAZINE is also employed in chemical research to explore new reaction pathways and develop innovative applications in various industries.

Upstream product

• 946-82-7 cyclohexanone phenylhydrazone 
• 7647-01-0 hydrogenchloride 
• 100-63-0 phenylhydrazine 
• 108-94-1 cyclohexanone 
• 108-91-8 cyclohexylamine 
• 102536-14-1 C₁₈H₁₆NO₂P 

Downstream Products

• 53656-73-8 1-Cyclohexyl-2-phenyl-1-(2,2,2-trifluorethylcarbimidoyl)-hydrazin 
• 53656-72-7 1-Cyclohexyl-2-phenyl-1-(2,2,2-trichlorethylcarbimidoyl)-hydrazin 
• 1086030-13-8 1-cyclohexyl-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbaldehyde 
• 1086031-05-1 C₂₁H₂₄N₂O₃ 
• 1086031-04-0 C₂₁H₂₆N₂O₄ 
• 1086027-32-8 N-(1-cyclohexyl-3-oxo-2-phenyl-2,3-dihydro-1H-indazole-5-carbonyl)-4-methoxybenzenesulfonamide 
• 1086027-81-7 2-chloro-N-(1-cyclohexyl-3-oxo-2-phenyl-2,3-dihydro-1H-indazole-5-carbonyl)-benzenesulfonamide 
• 1086025-82-2 (S)-2-[(1-cyclohexyl-3-oxo-2-phenyl-2,3-dihydro-1H-indazole-5-carbonyl)-amino]-3-(1H-indol-3-yl)-propionic acid methyl ester 
• 1086025-98-0 (S)-2-[(1-cyclohexyl-3-oxo-2-phenyl-2,3-dihydro-1H-indazole-5-carbonyl)-amino]-3-(1H-indol-3-yl)-propionic acid 
• 1086030-11-6 1-cyclohexyl-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 53656-76-1 1-Cyclohexy-2,4-diphenyl-1-phenylcarbimidoyl-semicarbazid 
• 946-81-6 Phenyl-azo-cyclohexan 

Relevant academic research and scientific papers

Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations

Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys

VIRAL POLYMERASE INHIBITORS

The present invention relates to viral polymerase inhibitors, in particular inhibitors of viral polymerases within the Flaviviridae family such as hepatitis C virus (HCV), processes for their preparation and their use in the treatment of infections.

Amberlyst-15(H+)-NaBH4-LiCl: An effective reductor for oximes and hydrazones

A simple and mild procedure reduces oximes and hydrazones on amberlyst 15(H+) support with LiCl-NaBH4 to the corresponding amines and hydrazines respectively in high yield and purity.

Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride. Studies on direct and indirect reductive amination procedures

Sodium triacetoxyborohydride is presented as a general reducing agent for the reductive amination of aldehydes and ketones. Procedures for using this mild and selective reagent have been developed for a wide variety of substrates. The scope of the reaction includes aliphatic acyclic and cyclic ketones, aliphatic and aromatic aldehydes, and primary and secondary amines including a variety of weakly basic and nonbasic amines. Limitations include reactions with aromatic and unsaturated ketones and some sterically hindered ketones and amines. 1,2-Dichloroethane (DCE) is the preferred reaction solvent, but reactions can also be carried out in tetrahydrofuran (THF) and occasionally in acetonitrile. Acetic acid may be used as catalyst with ketone reactions, but it is generally not needed with aldehydes. The procedure is carried out effectively in the presence of acid sensitive functional groups such as acetals and ketals; it can also be carried out in the presence of reducible functional groups such as C-C multiple bonds and cyano and nitro groups. Reactions are generally faster in DCE than in THF, and in both solvents, reactions are faster in the presence of AcOH. In comparison with other reductive amination procedures such as NaBH3CN/MeOH, borane-pyridine, and catalytic hydrogenation, NaBH(OAc)3 gave consistently higher yields and fewer side products. In the reductive amination of some aldehydes with primary amines where dialkylation is a problem we adopted a stepwise procedure involving imine formation in MeOH followed by reduction with NaBH4.