536753-42-1Relevant articles and documents
Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases
Bhuiyan, Mohammed P.I.,Kato, Tamaki,Okauchi, Tatsuo,Nishino, Norikazu,Maeda, Satoko,Nishino, Tomonori G.,Yoshida, Minoru
, p. 3438 - 3446 (2007/10/03)
A series of chlamydocin analogs with various carbonyl functionalities were designed and synthesized as histone deacetylase (HDAC) inhibitors. Chlamydocin is a cyclic tetrapeptide containing an epoxyketone surrogate in the side chain which makes it irrever