537048-31-0

Upstream product

• 108046-33-9 1-benzyl-1,2,3,4-tetrahydro-2-pyridinone 
• 100-46-9 benzylamine 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 537048-29-6 N-benzyl-3-[(4-methylphenyl)sulfonyl]-5-(4-chlorophenyl)-3,4-dihydro-2(1H)-pyridinone 
• 330173-08-5 N-benzyl-2-(4-methylphenylsulfonyl)acetamide 
• 1027187-26-3 1-benzyl-5-(4-chloro-phenyl)-6-hydroxy-3-(toluene-4-sulfonyl)-piperidin-2-one 
• 537048-28-5 N-benzyl-3-(4-chlorophenyl)-5-(4-methylphenylsulfonyl)piperidine-2,6-dione 

Downstream Products

• 41216-03-9 (RS)-5-(4-chlorophenyl)-2-piperidone 

Relevant academic research and scientific papers

Iridium-Catalyzed β-C(sp2)?H Borylation of Enamides – Access to 3,3-Dihalogeno-2-methoxypiperidines

An efficient catalytic preparation of synthetically useful new β-borylated enamides was achieved under relatively mild conditions via a regioselective iridium-catalyzed C(sp2)?H borylation. The method features broad substrate scope, good functi

Regioselective reduction of N-alkyl-3-sulfonylglutarimide. Formal synthesis of 1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine and homobaclofen

Reduction of N-alkyl-3-sulfonylglutarimides with (1) sodium hydride and then with lithium aluminum hydride, or (2) sodium borohydride yielded two different types of regioselectively reduced hydroxypiperidinones which were further dehydrated to two pyridin-2-ones in the presence of boron trifluoride etherate. Cycloaddition and regioselective reduction were combined to synthesize 1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine and homobaclofen.