53731-26-3

Basic information

• Product Name: 1-(Difluoromethyl)naphthalene
• Synonyms: 1-(Difluoromethyl)naphthalene
• CAS NO: 53731-26-3
• Molecular Formula: C₁₁H₈F₂
• Molecular Weight: 178.1780264
• Mol File: 53731-26-3.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Difluoromethyl)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Difluoromethyl)naphthalene(53731-26-3)
• EPA Substance Registry System: 1-(Difluoromethyl)naphthalene(53731-26-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 53731-26-3(Hazardous Substances Data)

Usage

General Description

1-(Difluoromethyl)naphthalene is a chemical compound with the molecular formula C11H8F2. It is a fluorinated derivative of naphthalene, which is a polycyclic aromatic hydrocarbon commonly found in coal tar and petroleum. 1-(Difluoromethyl)naphthalene is used as a building block in organic synthesis and as a precursor for the production of more complex molecular structures. It has a fluoromethyl group attached to the naphthalene ring, which gives it unique properties and potential applications in various fields such as pharmaceuticals, agrochemicals, and materials science. Due to its chemical structure and reactivity, 1-(Difluoromethyl)naphthalene is of interest to researchers and industries looking to develop new compounds with specific properties for a range of industrial and scientific applications.

Upstream product

• 66-77-3 1-naphthaldehyde 
• 91-20-3 naphthalene 
• 90-14-2 1-Iodonaphthalene 
• 75-45-6 Chlorodifluoromethane 
• 13922-41-3 1-Naphthylboronic acid 
• 1219454-89-3 2-((difluoromethyl)sulfonyl)pyridine 
• 7029-32-5 dinaphthalen-1-ylzinc 
• 275818-95-6 sodium difluoromethanesulfinate 
• 101539-62-2 1-naphthylmethyl-TPP 
• 1493-03-4 iododifluoromethane 
• 703-55-9 1-naphthylmagnesiumbromide 
• 90-11-9 1-Bromonaphthalene 
• 65864-64-4 trimethyl(difluoromethyl)silane 
• 90-13-1 1-Chloronaphthalene 

Downstream Products

• 90-12-0 1-Methylnaphthalene 

Relevant articles and documents

Electrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides

This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides under electrochemical conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems.

Ph2S/selectfluor-promoted deoxydifluorination of aldehydes

The installation of a HCF2 group is a research area that has received increasing attention, and deoxydifluorination of aldehydes have served as an attractive protocol due to the wide availability of aldehydes. Herein we describe a Ph2/sub

Deoxyfluorination of (Hetero)aryl Aldehydes Using Tetramethylammonium Fluoride and Perfluorobutanesulfonyl Fluoride or Trifluoromethanesulfonic Anhydride

This Communication describes the conversion of (hetero)aryl aldehydes into the corresponding (hetero)aryl difluoromethyl products using anhydrous NMe4F in combination with perfluorobutanesulfonyl fluoride or trifluoromethanesulfonic anhydride.