53755-58-1

Basic information

• Product Name: Drupanin
• Synonyms: (E)-3-[4-Hydroxy-3-(3-methyl-2-butenyl)phenyl]acrylic acid;3-(3-Methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid;3-Prenyl-4-hydroxycinnamic acid;3-Prenyl-4-hydroxy-trans-cinnamic acid;4-Hydroxy-3-(3-methyl-2-butenyl)cinnamic acid;Drupanin
• CAS NO: 53755-58-1
• Molecular Formula: C₁₄H₁₆O₃
• Molecular Weight: 232.27504
• Mol File: 53755-58-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 393.3°Cat760mmHg
• Flash Point: 205.8°C
• Appearance: /
• Density: 1.165g/cm³
• Vapor Pressure: 6.87E-07mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: Drupanin(CAS DataBase Reference)
• NIST Chemistry Reference: Drupanin(53755-58-1)
• EPA Substance Registry System: Drupanin(53755-58-1)

Safety Data

• Hazardous Substances Data: 53755-58-1(Hazardous Substances Data)

Usage

General Description

Drupanin is a chemical compound derived from the plant Drupacea. It is known for its potential medicinal properties due to its antifungal, antimicrobial, and antioxidant activities. Drupanin is being studied for its potential use in treating various health conditions such as cancer, inflammation, and infections. It has also shown promise in protecting cells from oxidative damage and promoting overall health and well-being. Further research is needed to fully understand the therapeutic potential of drupanin and its possible applications in medicine.

InChI:InChI=1/C14H16O3/c1-10(2)3-6-12-9-11(4-7-13(12)15)5-8-14(16)17/h3-5,7-9,15H,6H2,1-2H3,(H,16,17)/b8-5+

Upstream product

• 3943-97-3 methyl 4-hydroxycinnamate 
• 870-63-3 prenyl bromide 
• 1208233-14-0 tert-butyl (E)-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]acrylate 
• 7400-08-0 p-Coumaric Acid 
• 151071-04-4 4-iodo-2-(3-methylbut-2-en-1-yl)phenyl acetate 
• 151071-03-3 4-iodo-2-(3-methylbut-2-en-1-yl)phenol 
• 540-38-5 p-Iodophenol 
• 151071-02-2 methyl (E)-3-[4-(acetyloxy)-3-(3-methyl-2-butenyl)phenyl]-2-propenoate 
• 72704-01-9 (E)-methyl 3-[4-Hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]acrylate 

Downstream Products

• 1208233-09-3 drupanin phenethyl ester 
• 72704-01-9 (E)-methyl 3-[4-Hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]acrylate 

Relevant articles and documents

Palladium-Catalyzed Directed para C?H Functionalization of Phenols

Various practical methods for the selective C?H functionalization of the ortho and recently also of the meta position of an arene have already been developed. Following our recent development of the directing-group-assisted para C?H functionalization of toluene derivatives, we herein report the first remote para C?H functionalization of phenol derivatives by using a recyclable silicon-containing biphenyl-based template. The effectiveness of this strategy was illustrated with different synthetic elaborations and by the synthesis of various phenol-based natural products.

Artepillin C isoprenomics: Design and synthesis of artepillin C isoprene analogues as lipid peroxidation inhibitor having low mitochondrial toxicity

We designed and synthesized isoprene analogues of artepillin C, a major component of Brazilian propolis, and investigated the inhibitory activity on lipid peroxidation of rat liver mitochondria (RLM) and RLM toxicity based on isoprenomics. We succeeded in

Synthesis of Phenolic Natural Products Using Palladium Catalyzed Coupling Reactions

Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity.The scope of these reactions is explored.Palladium catalyzed reactions are employ