151071-02-2Relevant articles and documents
Artepillin C isoprenomics: Design and synthesis of artepillin C isoprene analogues as lipid peroxidation inhibitor having low mitochondrial toxicity
Uto, Yoshihiro,Ae, Shutaro,Koyama, Daisuke,Sakakibara, Mitsutoshi,Otomo, Naoki,Otsuki, Mamoru,Nagasawa, Hideko,Kirk, Kenneth L.,Hori, Hitoshi
, p. 5721 - 5728 (2007/10/03)
We designed and synthesized isoprene analogues of artepillin C, a major component of Brazilian propolis, and investigated the inhibitory activity on lipid peroxidation of rat liver mitochondria (RLM) and RLM toxicity based on isoprenomics. We succeeded in
The synthesis of Plicatin B via the Heck reaction
Bates,Gabel
, p. 3547 - 3550 (2007/10/02)
The anti-microbial natural product Plicatin B has been synthesized in 53% overall yield using a Heck reaction as the key step. The optimum conditions for this reaction have been determined. Halophenols proved much less reactive than their corresponding ac