53762-85-9Relevant academic research and scientific papers
Stereospecific synthesis of a new N-tosyl bromo-aminocyclitol
Kurbano?lu, Namudar ?zzet
, p. 95 - 99 (2017)
Abstract: Aminocyclitols are cyclic polyhydroxylated amines formally derived from cyclitols, and they constitute an important class of biologically active compounds. In the current research, the synthesis and characterization of a new N-tosyl bromo-aminoc
Collective Synthesis of Schilancidilactones A, B and Schilancitrilactones A, B, C, 20-epi-Schilancitrilactone A
Wang, Hengtao,Wang, Liang,Li, Yihang,Zhang, Xiunan,Tang, Pingping
, p. 255 - 268 (2019)
Schisandraceae triterpenoids are novel natural products that contain highly fused ring systems bearing multiple chiral centers surrounding. Some of them exhibit promising bioactivities, such as antitumor, anti-HIV, etc. In this article, we describe our ef
Synthesis of branched carbasugars via photooxygenation and manganese(III) acetate free radical cyclization
Altun, Yasemin,Dogan, Sengul Dilem,Balci, Metin
, p. 4884 - 4890 (2014)
Transformation of cyclohexa-1,3- and 1,4-dienes to carbasugars is described. Photooxygenation of dienes gave bicyclic endoperoxides, which were reduced with thiourea to the corresponding 1,4-diols with cis-configuration. Lactonization of the remaining dou
Unusual Oxidative Dealkylation Strategy toward Functionalized Phenalenones as Singlet Oxygen Photosensitizers and Photophysical Studies
De Bonfils, Paul,Verron, Elise,Sandoval-Altamirano, Catalina,Jaque, Pablo,Moreau, Xavier,Gunther, German,Nun, Pierrick,Coeffard, Vincent
, p. 10603 - 10616 (2020/09/23)
A series of functionalized 6-alkoxy phenalenones was prepared through an unprecedented oxidative dealkylation of readily available phenalene precursors. The starting phenalenes were efficiently synthesized via an aminocatalyzed annulation/O-alkylation str
Reductive Difunctionalization of Aryl Alkenes with Sodium Metal and Reduction-Resistant Alkoxy-Substituted Electrophiles
Fukazawa, Mizuki,Nogi, Keisuke,Sasamori, Takahiro,Takahashi, Fumiya,Yorimitsu, Hideki
supporting information, (2020/03/13)
A general method for alkali-metal-promoted reductive difunctionalization of alkenes has been developed by means of reduction-resistant alkoxy-substituted electrophiles. A series of 1,2-diboration and 1,2-dicarbofunctionalization products can be synthesize
A Pd-catalyzed asymmetric allylic substitution cascade: Via an asymmetric desymmetrization for the synthesis of bicyclic dihydrofurans
Xu, Kai,Liu, Hao,Hou, Yilin,Shen, Jiefeng,Liu, Delong,Zhang, Wanbin
supporting information, p. 13295 - 13298 (2019/11/13)
A Pd-catalyzed asymmetric allylic substitution cascade of allylic meso-dicarbonates with 3-oxo-nitriles has been developed for the synthesis of chiral bicyclic dihydrofurans bearing two vicinal carbon stereocenters. The reaction proceeds via an asymmetric desymmetrization process with the desired products being obtained in high yields and with up to 97% ee. The reaction was performed on a gram-scale and the corresponding bicyclic dihydrofurans could undergo several transformations. The methodology provides an efficient synthetic route to biologically active chiral bicyclic dihydrofurans derivatives.
Amine Catalysis for the Organocatalytic Diboration of Challenging Alkenes
Farre, Albert,Soares, Kaline,Briggs, Rachel A.,Balanta, Angelica,Benoit, David M.,Bonet, Amadeu
supporting information, p. 17552 - 17556 (2016/11/28)
The generation of in situ sp2–sp3diboron adducts has revolutionised the synthesis of organoboranes. Organocatalytic diboration reactions have represented a milestone in terms of unpredictable reactivity of these adducts. However, current methodologies have limitations in terms of substrate scope, selectivity and functional group tolerance. Here a new methodology based on the use of simple amines as catalyst is reported. This methodology provides a completely selective transformation overcoming current substrate scope and functional/protecting group limitations. Mechanistic studies have been included in this report.
Total synthesis of schilancitrilactones B and C
Wang, Liang,Wang, Hengtao,Li, Yihang,Tang, Pingping
supporting information, p. 5732 - 5735 (2015/09/21)
The first total syntheses of schilancitrilactones B and C have been accomplished in 17 steps (longest linear sequence) from commercially available materials. Key steps include an intramolecular radical cyclization to provide the seven-membered ring, late-stage iodination, and an intermolecular radical addition reaction to complete the total synthesis. In step: The first total syntheses of schilancitrilactones B and C have been accomplished by using an intramolecular radical cyclization to provide the seven-membered ring, late-stage iodination, and an intermolecular radical addition reaction as key steps. The approach provides a sequence for the syntheses of compounds related to the schilancitrilactones, as well as their derivatives and analogues.
Composition
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, (2007/10/13)
PROBLEM TO BE SOLVED: To provide a hair dye composition which has excellent hair-bleaching power and little damages hair. SOLUTION: This hair dye composition comprises (a) a first agent containing a nitrogen-containing compound represented by the general formula (1) [R1, R3to R5are each H, OH, a ≤12C alkyl which may have one or more substituents, or the like; R2is OH, -R or -OR (R is the same meaning as R3to R5); two or more of R1to R5may together form a 3 to 8-membered ring which may have one or more substituents] or its salt and (b) a second agent containing an oxidizing agent, and has pH 7.5 to 12, when used. COPYRIGHT: (C)2007,JPOandINPIT
Expanding the scope of biomass-derived chemicals through tandem reactions based on oxorhenium-catalyzed deoxydehydration
Shiramizu, Mika,Toste, F. Dean
supporting information, p. 12905 - 12909 (2014/01/06)
New modes of DODH: Oxorhenium compounds act as deoxydehydration(DODH)/acid dual-purpose catalysts to transform biomass-derived diol substrates into a variety of commodity chemical precursors. The power of this approach is highlighted by a tandem [1,3]-OH shift/DODH of 2-ene-1,4-diols and 2,4-diene-1,6-diols, and by a DODH/esterification sequence of sugar acids to unsaturated esters for the production of polymers and plasticizers. Copyright
