53872-19-8

Basic information

• Product Name: 4-Carbomethoxy-5-methoxy-2-phenyl-1,3-oxazole
• Synonyms: 4-Carbomethoxy-5-methoxy-2-phenyl-1,3-oxazole;methyl 5-methoxy-2-phenyl-1,3-oxazole-4-carboxylate
• CAS NO: 53872-19-8
• Molecular Formula: C₁₂H₁₁NO₄
• Molecular Weight: 233.22004
• Mol File: 53872-19-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Carbomethoxy-5-methoxy-2-phenyl-1,3-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Carbomethoxy-5-methoxy-2-phenyl-1,3-oxazole(53872-19-8)
• EPA Substance Registry System: 4-Carbomethoxy-5-methoxy-2-phenyl-1,3-oxazole(53872-19-8)

Safety Data

• Hazardous Substances Data: 53872-19-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron, 49, p. 5445, 1993 DOI: 10.1016/S0040-4020(01)87261-6Tetrahedron Letters, 27, p. 5559, 1986 DOI: 10.1016/S0040-4039(00)85265-X

Upstream product

• 1132667-77-6 dimethyl 3-phenyl-1-tosylaziridine-2,2-dicarboxylate 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 108-59-8 malonic acid dimethyl ester 
• 145838-86-4 bis(methoxycarbonyl)(phenyliodinio)methanide 
• 100-47-0 benzonitrile 
• 6773-29-1 dimethyl diazomalonate 

Downstream Products

• 53872-14-3 5-methoxy-2-phenyl-oxazole-4-carboxylic acid tert-butylamide 
• 53872-15-4 5-methoxy-2-phenyl-oxazole-4-carboxylic acid dimethylamide 
• 53872-38-1 5-methylamino-2-phenyl-oxazole-4-carboxylic acid methyl ester 
• 53872-13-2 5-methoxy-2-phenyl-oxazole-4-carboxylic acid methylamide 
• 54644-11-0 5-methoxy-2-phenyl-oxazole-4-carbonyl chloride 
• 53872-37-0 5-(4-methoxy-anilino)-2-phenyl-oxazole-4-carboxylic acid methyl ester 
• 53872-36-9 5-(4-methyl-anilino)-2-phenyl-oxazole-4-carboxylic acid methyl ester 
• 53872-02-9 5-dimethylamino-2-phenyl-oxazole-4-carboxylic acid methyl ester 
• 53872-33-6 2-phenyl-5-(3-trifluoromethyl-anilino)-oxazole-4-carboxylic acid methyl ester 
• 53872-32-5 2-phenyl-5-(4-trifluoromethyl-anilino)-oxazole-4-carboxylic acid methyl ester 
• 53872-08-5 5-methoxy-2-phenyl-oxazole-4-carboxylic acid 3-trifluoromethyl-anilide 
• 53872-07-4 5-methoxy-2-phenyl-oxazole-4-carboxylic acid 4-trifluoromethyl-anilide 
• 53872-12-1 5-methoxy-2-phenyl-oxazole-4-carboxylic acid 4-methoxy-anilide 
• 53872-09-6 5-methoxy-2-phenyl-oxazole-4-carboxylic acid 3-chloro-anilide 

Relevant articles and documents

Nickel(II)-catalyzed diastereoselective [3+2] cycloaddition of N-tosyl-aziridines and aldehydes via selective carbon-carbon bond cleavage

An efficient and mild Ni(ClO4)2-catalyzed [3+2] cycloaddition of N-tosylaziridines and aldehydes via C-C bond cleavage was developed. The cycloaddition reaction proceeds with high diastereoselectivity and regioselectivity leading to

RhII-catalyzed cycloadditions of carbomethoxy iodonium ylides

Carbomethoxy iodonium ylides, generated from methyl acetoacetate and methyl malonate, respectively, are exploited in synthesis of cyclopropanes, cyclopropenes as well as various heterocycles.

Rhodium-catalyzed heterocycloaddition route to 1,3-oxazoles as building blocks in natural products synthesis

Rhodium(II) acetate serves as a catalyst for the heterocycloaddition reaction of diazodicarbonyl compounds with nitriles to give functionalized 1,3-oxazole derivatives in a simple one-step procedure. In particular, dimethyl diazomalonate undergoes this re