59171-72-1

Basic information

• Product Name: 2-PHENYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 2-PHENYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER;Methyl 2-phenyloxazole-4-carboxylate;4-Oxazolecarboxylic acid, 2-phenyl-, methyl ester
• CAS NO: 59171-72-1
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19
• Mol File: 59171-72-1.mol
• Article Data: 21

Chemical Properties

• Melting Point: 85.5-87 °C
• Boiling Point: 327.1±34.0 °C(Predicted)
• Appearance: /
• Density: 1.204±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.87±0.10(Predicted)
• CAS DataBase Reference: 2-PHENYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER(59171-72-1)
• EPA Substance Registry System: 2-PHENYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER(59171-72-1)

Safety Data

• Hazardous Substances Data: 59171-72-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 5759, 1993 DOI: 10.1021/jo00073a040

Upstream product

• 55044-06-9 methyl 2-phenyl-2-oxazoline-4-carboxylate 
• 78715-83-0 methyl (S)-2-phenyl-4,5-dihydrooxazole-4-carboxylate 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 100-52-7 benzaldehyde 
• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 10144-46-4 N-benzoyl-L-serine methyl ester 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 932-90-1 Benzaldoxime 
• 100-47-0 benzonitrile 
• 153180-14-4 Dimethyl benzamido<(phenylthio)methyl>malonate 
• 5873-90-5 methyl benzimidate hydrochloride 
• 20989-42-8 N-benzoylserine methyl ester 
• 153180-31-5 2-Phenyl-5-phenylsulfanyl-oxazole-4,4-dicarboxylic acid dimethyl ester 

Downstream Products

• 1370731-81-9 N-benzyl-2,5-diphenyloxazole-4-formamide 
• 92-71-7 2,5-diphenyloxazole 
• 18735-78-9 2,5-diphenyloxazole-4-carboxylic acid 
• 2549-35-1 2,5-diphenyl-4-hydroxymethyloxazole 
• 1370731-73-9 methyl 2-phenyl-5-(2,5-dimethylphenyl)oxazole-4-carboxylate 
• 1370731-78-4 C₁₇H₈⁽²⁾H₅NO₃ 
• 1370731-75-1 methyl 2-phenyl-5-(3-nitrophenyl)oxazole-4-carboxylate 
• 1370731-67-1 methyl 2-phenyl-5-(3,4-dichlorophenyl)oxazole-4-carboxylate 
• 1370731-68-2 methyl 2-phenyl-5-(2,3-dichlorophenyl)oxazole-4-carboxylate 
• 1370731-61-5 methyl 2-phenyl-5-(4-methylphenyl)oxazole-4-carboxylate 
• 1370731-62-6 methyl 2-phenyl-5-(3-methylphenyl)oxazole-4-carboxylate 
• 25755-94-6 methyl 2,5-diphenyloxazole-4-carboxylate 
• 1370731-50-2 C₂₂H₁₆N₂O₆ 
• 1383581-70-1 2-phenyl-1,3-oxazole-4-carbohydroxamic acid 

Relevant articles and documents

Substituted N - ((1 °, 3° - [...] - 4° - yl) - methyl) - 4 - benzoyl piperidine compound and use thereof

The invention discloses a substituted N-((1', 3'-azole-4'-yl)-methyl)-4-benzoyl-hexahydropyridine compound represented by formula I, a preparation method thereof, and applications of the substituted N-((1', 3'-oxazole-4'-yl)-methyl)-4-benzoyl-hexahydropyridine compound in preparation of antituberculous drugs. The substituted N-((1', 3'-azole-4'-yl)-methyl)-4-benzoyl-hexahydropyridine compound possesses activity on mycobacterium tuberculosis-susceptible strains, and also possesses activity on strains with tolerance on traditional first-line antituberculous drugs such as isoniazide and rifampicin, and is a novel mycobacterium tuberculosis resistant compound with a promising application prospect.

The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions

A rapid flow synthesis of oxazolines and their oxidation to the corresponding oxazoles is reported. The oxazolines are prepared at room temperature in a stereospecific manner, with inversion of stereochemistry, from β-hydroxy amides using Deoxo-Fluor. The

I2-Catalyzed C-O Bond Formation and Dehydrogenation: Facile Synthesis of Oxazolines and Oxazoles Controlled by Bases

A general method for the synthesis of oxazolines and oxazoles was developed through I2-catalyzed C-O bond formation and dehydrogenation with the same oxidant, TBHP. By simply tuning reaction bases, either oxazolines or oxazoles were selectively