53929-74-1

Usage

Uses

Used in Organic Synthesis:
(3-Bromo-propyl)-dimethyl-amine is used as a building block in the synthesis of various complex organic compounds. Its presence of an amine and bromo group allows for a wide range of chemical reactions, making it a valuable component in the creation of diverse chemical structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (3-Bromo-propyl)-dimethyl-amine is used as a key intermediate in the development of new drugs. Its reactivity and ability to form various chemical structures make it a promising candidate for the synthesis of pharmaceutical compounds with potential therapeutic applications.
Used in Chemical Research:
(3-Bromo-propyl)-dimethyl-amine is utilized in chemical research as a versatile reagent for studying various chemical reactions and mechanisms. Its unique structure and reactivity provide researchers with valuable insights into the behavior of different chemical systems and contribute to the advancement of chemical knowledge.
Used in Industrial Applications:
In industrial applications, (3-Bromo-propyl)-dimethyl-amine serves as a crucial component in the production of various chemicals and materials. Its versatility and reactivity make it suitable for use in the synthesis of a wide range of industrial products, including specialty chemicals, polymers, and other materials with specific properties and applications.

InChI:InChI=1/C5H12BrN/c1-7(2)5-3-4-6/h3-5H2,1-2H3

Upstream product

• 20904-57-8 N,N-dimethyl-3-phenoxypropan-1-amine 
• 3179-63-3 3-Dimethylamino-1-propanol 

Downstream Products

• 729-21-5 dimethyl-[3-(4-phenyl-piperazin-1-yl)-propyl]-amine 
• 57860-52-3 [4-(3,5-Dimethoxy-phenyl)-pentyl]-dimethyl-amine 
• 66897-56-1 N-(2-Chloro-benzoyl)-N-(3-dimethylamino-propyl)-benzenesulfonamide 
• 5378-20-1 [3-(4-chloro-2-[1,3,4]oxadiazol-2-yl-phenoxy)-propyl]-dimethyl-amine 
• 137296-31-2 1-(3-Dimethylamino-propyl)-7-(4-methoxy-benzyl)-3-propyl-3,7-dihydro-purine-2,6-dione 
• 155249-98-2 5-Chloro-2-(4-chloro-2-nitro-phenyl)-1-(3-dimethylamino-propyl)-1H-indole-3-carbaldehyde 
• 95930-58-8 2-(3-Dimethylamino-propyl)-1-phenyl-isothiourea; compound with oxalic acid 
• 1221858-71-4 C₁₆H₁₆F₃N₅O₂ 
• 1245927-54-1 C₂₈H₂₉ClN₆O₂S 
• 303-49-1 Clomipramine 
• 113806-05-6 olopatadine 
• 95554-73-7 5-(3-dimethylamino-propyl)-2-phenyl-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 

Relevant academic research and scientific papers

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

On the basis of deguelin, a series of the B,C-ring truncated surrogates with N-substituted amide linkers were investigated as HSP90 inhibitors. The structure activity relationship of the template was studied by incorporating various substitutions on the nitrogen of the amide linker and examining their HIF-1α inhibition. Among them, compound 57 showed potent HIF-1α inhibition and cytotoxicity in triple-negative breast cancer lines in a dose-dependent manner. Compound 57 downregulated expression and phosphorylation of major client proteins of HSP90 including AKT, ERK and STAT3, indicating that its antitumor activity was derived from the inhibition of HSP90 function. The molecular modeling of 57 demonstrated that 57 bound well to the C-terminal ATP-binding pocket in the open conformation of the hHSP90 homodimer with hydrogen bonding and pi-cation interactions. Overall, compound 57 is a potential antitumor agent for triple-negative breast cancer as a HSP90 C-terminal inhibitor.

INHIBITORS OF ACETYL-COA CARBOXYLASE

The present invention relates to compounds that act as acetyl-CoA carboxylase (ACC) inhibitors. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.