53981-69-4

Basic information

• Product Name: 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL
• Synonyms: 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL;Ethanone, 1-(1H-imidazol-2-yl)- (9CI);2-ACETYLIMIDAZOLE;1-(1H-imidazol-2-yl)ethanone(SALTDATA: FREE);1-(1H-Imidazol-2-yl)-1-ethanone
• CAS NO: 53981-69-4
• Molecular Formula: C₅H₆N₂O
• Molecular Weight: 110.11394
• Product Categories: ACETYLGROUP
• Mol File: 53981-69-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 136-138℃
• Boiling Point: 269.4 °C at 760 mmHg
• Flash Point: 120.8 °C
• Appearance: /
• Density: 1.19 g/cm³
• Vapor Pressure: 0.00727mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 11.11±0.10(Predicted)
• CAS DataBase Reference: 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL(53981-69-4)
• EPA Substance Registry System: 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL(53981-69-4)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 53981-69-4(Hazardous Substances Data)

Usage

General Description

1-(1H-Imidazol-2-yl)-ethanone HCl, also known as 2-Imidazolyl ethanone hydrochloride, is a chemical compound with the molecular formula C5H7NO.HCl. It is a derivative of imidazole, a five-membered aromatic ring containing two nitrogen atoms. 1-(1H-IMIDAZOL-2-YL)-ETHANONE HCL is commonly used as a reagent in organic synthesis and pharmaceutical research. It is also used in the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals. Its properties and structure make it suitable for various applications in the field of chemistry and biotechnology.

InChI:InChI=1/C5H6N2O/c1-4(8)5-6-2-3-7-5/h2-3H,1H3,(H,6,7)

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 1100723-54-3 (Z)-1-(2-phenylhydrazono)-1-(1H-1,2,3-triazol-1-yl)propanone 
• 1100723-55-4 (Z)-1-[2-(4-chlorophenyl)hydrazono]-1-(1H-1,2,3-triazol-1-yl)propanone 
• 1100723-57-6 (Z)-1-[2-(p-tolyl)hydrazono]-1-(1H-1,2,3-triazol-1-yl)propanone 
• 875553-56-3 1-(1-tosyl-1H-imidazol-2-yl)ethan-1-one 
• 127-19-5 N,N-dimethyl acetamide 
• 61278-81-7 1-(diethoxymethyl)-1H-imidazole 
• 22098-61-9 1-(1H-imidazol-2-yl)ethan-1-ol 
• 75-16-1 methylmagnesium bromide 
• 31722-49-3 2-cyano imidazole 

Downstream Products

• 951214-13-4 (E)-N-(1-(1H-imidazol-2-yl)ethylidene)prop-2-en-1-amine 
• 875553-56-3 1-(1-tosyl-1H-imidazol-2-yl)ethan-1-one 
• 1394118-86-5 4-[1-(2-aminopyrimidin-4-yl)-3-methyl-1H-indazol-6-yl]-2-(1H-imidazol-2-yl)but-3-yn-2-ol 
• 22098-61-9 1-(1H-imidazol-2-yl)ethan-1-ol 

Relevant articles and documents

Generation and Lithiation of the Dimers of 6-(Dimethylamino)-1,4-diazafulvene. A Novel Synthesis of 2-Alkanoylimidazoles

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Gas-phase pyrolysis in organic synthesis: New route for synthesis of functionally substituted imidazoles

(Chemical Equation Presented) 1,2,3-Triazolylpropanone was prepared and coupled with aryldiazonium salts yielding the corresponding arylhydrazones. Gas-phase pyrolysis of the hydrazono derivative produced N-arylamino-2- acetylimidazole as well as 2-acetyl

PYRAZOLE DERIVATIVE

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.