53984-17-1

Upstream product

• 100-42-5 styrene 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 27652-35-3 (E)-2-styrylaniline 
• 117632-84-5 1-((trifluoromethyl)sulfonyl)-1H-benzo[d][1,2,3]triazole 
• 615-36-1 2-bromoaniline 
• 1100-88-5 benzyltriphenylphosphonium chloride 
• 552-89-6 2-nitro-benzaldehyde 

Relevant academic research and scientific papers

Palladium-catalyzed denitrogenative functionalizations of benzotriazoles with alkenes and 1,3-dienes

Pd-Catalyzed denitrogenative functionalizations of benzotriazoles with alkenes and 1,3-dienes have been developed, which enable the rapid access of diverse ortho-amino styrenes and 2-vinylindolines, respectively. This study shows the great potential of benzotriazoles as a [1C]-synthon in cross-coupling reactions and an aza-[3C]-synthon in cycloaddition reactions.

Metal-free C-H amination for indole synthesis

An effective metal-free C-H amination of N-Ts-2-alkenylanilines by using DDQ as an oxidant has been developed to afford a diverse range of substituted indoles. This protocol is operationally simple and robust, obviates the need of expensive transition-metal catalysts, and offers a broad substrate scope. A mechanism involving a radical cation generated by SET and a migratorial process via a phenonium ion intermediate is proposed.