53995-78-1Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS
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Paragraph 0236, (2016/11/07)
Heterocyclic compounds and methods of making them and using them.
Novel benzofurans and indols
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Page/Page column 6, (2008/06/13)
Compounds of formula (I) wherein X is a fluorine or a chlorine atom; the methyl groups located at the 2- and 5-position of the piperazine ring are in trans-configuration to each other; Y is NH or O; R1 is selected front hydrogen, chloro, bromo,
USE OF INDOLYL DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT ALLERGIC RHINITIS
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Page/Page column 78-79, (2008/06/13)
A method to treat allergic rhinitis is disclosed in which patients are administered certain indolyl compounds.
Heterocyclic compounds
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, (2008/06/13)
Heterocyclic compounds and methods of making them and using them.
Tripeptidyl peptidase inhibitors
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Page column 26, (2010/11/29)
The invention is relative to a compound of formula (I) and its use as an inhibitor of the CCK-inactivating peptidase tripeptidyl peptidase (TPP II). The invention concerns in particular the treatment of eating disorder, obesity, psychotic syndrome and associated psychiatric disorders. It concerns also the cosmetic use of a compound (I) in particular to aid slimming.
Indole derivatives for the treatment of osteoporosis
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, (2008/06/13)
The invention relates to indole compounds, a process for preparing, pharmaceutical compositions containing the compounds and treating diseases associated with over activity of osteoclasts.
5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: Novel and selective inhibitors of the vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity
Gagliardi, Stefania,Nadler, Guy,Consolandi, Emanuela,Parini, Carlo,Morvan, Marcel,Legave, Marie-N?elle,Belfiore, Pietro,Zocchetti, Andrea,Clarke, Geoffrey D.,James, Ian,Nambi, Ponnal,Gowen, Maxine,Farina, Carlo
, p. 1568 - 1573 (2007/10/03)
The vacuolar H+-ATPase (V-ATPase), located on the ruffled border of the osteoclast, is a proton pump which is responsible for secreting the massive amounts of protons that are required for the bone resorption process. With the aim to identify n
