7494-45-3

Basic information

• Product Name: 4,5-DICHLORO-2-NITROTOLUENE
• Synonyms: 4,5-DICHLORO-2-NITROTOLUENE;1,2-DICHLORO-4-METHYL-5-NITRO-BENZENE;4,5-Dichloro-2-Methylnitrobenzene;7494-45-3;Benzene, 1,2-dichloro-4-methyl-5-nitro-
• CAS NO: 7494-45-3
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.03
• Mol File: 7494-45-3.mol

Chemical Properties

• Melting Point: 62 °C
• Boiling Point: 277.1 °C at 760 mmHg
• Flash Point: 121.4 °C
• Appearance: /
• Density: 1.456 g/cm³
• Vapor Pressure: 0.00778mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4,5-DICHLORO-2-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DICHLORO-2-NITROTOLUENE(7494-45-3)
• EPA Substance Registry System: 4,5-DICHLORO-2-NITROTOLUENE(7494-45-3)

Safety Data

• Hazardous Substances Data: 7494-45-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4,5-DICHLORO-2-NITROTOLUENE is used as a reagent for the synthesis of N-hydroxyindole-2-carboxylates, which are inhibitors of lactate dehydrogenase (LDH). These inhibitors play a crucial role in controlling cancer cell proliferation, making 4,5-DICHLORO-2-NITROTOLUENE a valuable asset in the development of anticancer drugs.
Used in Biotechnology Industry:
In the biotechnology sector, 4,5-DICHLORO-2-NITROTOLUENE is utilized in the preparation of polyhalogenated quinoline C-nucleosides. These compounds have the potential to serve as antiviral agents, contributing to the development of new treatments for viral infections.
Used in Research:
4,5-DICHLORO-2-NITROTOLUENE is also suitable for LDH-related research, providing a foundation for further exploration into the mechanisms of lactate dehydrogenase and its role in various diseases, including cancer. By understanding the interactions between 4,5-DICHLORO-2-NITROTOLUENE and LDH, researchers can gain insights into the development of more effective therapies for cancer and other LDH-related conditions.

InChI:InChI=1/C7H5Cl2NO2/c1-4-2-5(8)6(9)3-7(4)10(11)12/h2-3H,1H3

Upstream product

• 95-75-0 3,4-Dichlorotoluene 
• 89-69-0 2,4,5-Trichloronitrobenzene 
• 996-82-7 sodium diethylmalonate 
• 70902-72-6 2-chloro-5-methyl-4-nitroaniline 
• 70343-10-1 2,5-dinitro-4-methylaniline 

Downstream Products

• 229481-09-8 (E)-2-(4,5-dichloro-2-nitrophenyl)-N,N-dimethylethenamine 
• 439612-43-8 5-(2-chloro-6-methyl-4-nitrophenoxy)-3-isopropyl-1H-indole 
• 121859-57-2 5,6-dichloro-1H-indole 
• 1209183-93-6 tert-butyl 5,6-dichloro-1H-indole-1-carboxylate 
• 863640-51-1 4,5-dichloro-2-nitrobenzyl dibromide 
• 93213-80-0 4,5-dichloro-2-nitrobenzyl bromide 
• 685535-05-1 1-chloro-2-(2-methoxyethoxy)-4-methyl-5-nitrobenzene 
• 685535-12-0 4-(2-chloro-5-methyl-4-nitrophenyl)-morpholine 
• 6639-30-1 2,4,5-trichlorotoluene 
• 50-82-8 2,4,5-trichlorobenzoic acid 
• 138992-15-1 dimethyl 2-(2-amino-4,5-dichlorophenyl)-1-<4-(methylimidazo<4,5-c>pyrid-1-yl)phenyl>ethylmalonate 
• 53995-78-1 5,6-Dichloro-1H-indole-2-carboxylic acid ethyl ester 
• 548448-72-2 (E)-6-O-(tert-butyldimethylsilyl)-1-(4,5-dichloro-2-nitrophenyl)-1,2-dideoxy-3,4-O-isopropylidene-D-allo-1-enitol 
• 548448-70-0 (Z)-6-O-(tert-butyldimethylsilyl)-1-(4,5-dichloro-2-nitrophenyl)-1,2-dideoxy-3,4-O-isopropylidene-D-allo-1-enitol 

Relevant articles and documents

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