54023-37-9

Upstream product

• 100-42-5 styrene 
• 674-82-8 4-methyleneoxetan-2-one 
• 1801-77-0 oxovanadium(V) ethoxydichloride 
• 89415-67-8 ethyl 2,2-dibromoacetoacetate 
• 141-97-9 ethyl acetoacetate 
• 75326-15-7 (2-bromo-1-phenylethyl)dimethylsulphonium bromide 
• 72174-84-6 ethyl 1-acetyl-2-phenylcyclopropanecarboxylate 
• 104690-31-5 ethyl 2-iodo-3-oxobutanoate 

Relevant academic research and scientific papers

Transition metal-free generation of the acceptor/acceptor-carbene: Via α-elimination: Synthesis of fluoroacetyl cyclopropanes

An efficient transition metal-free approach for the generation of acceptor/acceptor-carbene followed by trapping with alkenes to provide fluoroacetyl cyclopropanes has been described. The resulting cyclopropanes could be further converted into the fluorom

Organocatalytic Cloke-Wilson Rearrangement: DABCO-Catalyzed Ring Expansion of Cyclopropyl Ketones to 2,3-Dihydrofurans

An organocatalytic Cloke-Wilson rearrangement of cyclopropyl ketones to 2,3-dihydrofurans is exploited utilizing the homoconjugate addition process. With 1,4-diazabicyclo[2.2.2]octane as the catalyst, the rearrangement in DMSO at 120 °C proceeded in gener

Evidence of CuI/CuII Redox Process by X-ray Absorption and EPR Spectroscopy: Direct Synthesis of Dihydrofurans from β-Ketocarbonyl Derivatives and Olefins

The CuI/CuII and CuI/CuIII catalytic cycles have been subject to intense debate in the field of copper-catalyzed oxidative coupling reactions. A mechanistic study on the CuI/CuII redox proc

Manganese(II)- and (III)-mediated Free-radical Cyclisation of Alkenes, β-Keto Esters and Molecular Oxygen

The reactions of substituted ethenes with β-keto esters in the presence of a mixture of manganese(II) and manganese(III) acetates, and molecular oxygen yielded substituted 1,2-dioxan-3-ols 3 in 14-95percent yields.Cobalt(III) acetate, potassium permanganate, lead(IV) acetate, copper(II) acetate, chromium(VI) trioxide, thallium(III) acetate, ammonium cerium(IV) nitrate and iron(III) perchlorate were also used in place of manganese(III) acetate.Effects on the product yields of substituents in the alkenes and β-keto esters have been examined and reaction mechanisms are discussed.

VO(OR)Cl2-induced cyclization of diketene via ring opening

Diketene undergoes a VO(OR)Cl2-induced cyclization with styrenes via ring opening to give 3-alkoxycarbonyl-2-methyl-5-phenyl-4,5-dihydrofurans.Desilylative aromatization to the furans is observed in the reaction with α-trimethylsilylstyrene.

Formation of 1,2-dioxacyclohexanes by the reaction of alkenes with tris(2,4-pentanedionato)manganese(III) or with β-ketocarbonyl compounds in the presence of manganese(III) acetate

The reactions of 1,1-disubstituted ethenes, styrene, 1-octene, 1-nonene, cyclohexene and cyclooctene with tris(2,4-pentanedionato)manganese(III) in acetic acid at room temperature give 4-acetyl-3-hydroxy-3-methyl-1,2-dioxacyclohexanes in 8-92% yields. The

Oxidative Addition of 1,3-Dicarbonyl Compounds to Conjugated Olefins

A convenient one step synthesis of the 5-aryl- or 5-(1-alkenyl)-4,5-dihydrofurans from 1,3-dicarbonyl compounds and conjugated olefins in the presence of copper(II) chloride/pyridine or copper(II) chloride/pyridine/oxygen is reported.

Regioselective Synthesis of Dihydrofurans from 2,2-Dibromo 1,3-Diones and Olefins Using Copper

2,2-Dibromo 1,3-diones reacted with copper powder and olefin to give 2,3-dihydrofuran derivatives in a highly regioselective fashion.Acetylenes and 1,3-dienes also reacted with 2,2-dibromo 1,3-diones and copper to afford furan derivatives and 2-vinyl-2,3-

REGIOSELECTIVE SYNTHESIS OF DIHYDROFURANS FROM 2,2-DIBROMO-1,3-DIKETONE AND OLEFIN USING COPPER

2,2-Dibromo-1,3-diketones reacted with copper powder and olefin to give 4,5-dihydrofuran derivatives in a highly regioselective fashion.