54105-61-2

Basic information

• Product Name: Isoquinoline, 1,2,3,4-tetrahydro-2-(2-phenylethyl)-
• CAS NO: 54105-61-2
• Molecular Formula: C17H19N
• Molecular Weight: 237.345
• Mol File: 54105-61-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Isoquinoline, 1,2,3,4-tetrahydro-2-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 1,2,3,4-tetrahydro-2-(2-phenylethyl)-(54105-61-2)
• EPA Substance Registry System: Isoquinoline, 1,2,3,4-tetrahydro-2-(2-phenylethyl)-(54105-61-2)

Safety Data

• Hazardous Substances Data: 54105-61-2(Hazardous Substances Data)

Upstream product

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 622-24-2 2-phenylethyl chloride 
• 103-63-9 1-phenyl-2-bromoethane 
• 10165-99-8 2-(2-Phenylethyl)-isocarbostyril 
• 100-52-7 benzaldehyde 
• 60-12-8 2-phenylethanol 
• 1203602-82-7 (E)-N-styryl-1,2,3,4-tetrahydroisoquinoline 
• 82746-02-9 1-phenethylaminoisochroman 
• 64-04-0 phenethylamine 
• 75802-22-1 1-ethoxyisochromane 
• 4702-34-5 isochroman-1-one 
• 100-42-5 styrene 
• 103-82-2 phenylacetic acid 
• 95711-85-6 N-(2-Phenylethyl)-2-(2-hydroxyethyl)-benzamid 

Downstream Products

• 1312343-60-4 4-((5-methylfuran-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1312343-61-5 4-hexyl-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-62-3 4-(benzofuran-2-ylmethyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-65-6 4-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)furan-2-yl)benzonitrile 
• 1370354-63-4 4-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)furan-2-yl)benzaldehyde 
• 1370354-75-8 4-((5-(naphthalen-1-yl)thiophen-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-74-7 3-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)thiophen-2-yl)benzonitrile 
• 1370354-73-6 4-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)thiophen-2-yl)benzonitrile 
• 1370354-71-4 4-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)thiophen-2-yl)benzaldehyde 
• 1370354-70-3 4-((5-(4-nitrophenyl)furan-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-68-9 4-((5-(naphthalen-1-yl)furan-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-66-7 3-(5-((2-phenethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-methyl)furan-2-yl)benzonitrile 
• 1370354-60-1 4-((3-methylthiophen-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 
• 1370354-57-6 4-((1-methyl-1H-pyrrol-2-yl)methyl)-2-phenethyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines

A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is

Ru-catalyzed β-selective and enantioselective addition of amines to styrenes initiated by direct arene-exchange

A catalytic β-selective addition of amines to styrenes proceeded in the presence of cationic Ru complexes combined with diphosphine ligands. In the reaction of α-methylstyrene, an enantioselective addition was achieved by using xylylBINAP.

Broadening the scope of group 4 hydroamination catalysis using a tethered ureate ligand

(Chemical Equation Presented) A broadly applicable group-4-based precatalyst for the hydroamination of primary and secondary amines was developed. Screening experiments involving a series of amide and urea proligands led to the discovery of a tethered bis(ureate) zirconium complex with unprecedented reactivity in the intermolecular hydroamination of alkynes and the intramolecular hydroamination of alkenes. This catalyst system is effective with primary and secondary amines, 1,2-disubstituted alkenes, and heteroatom-containing functional groups, including ethers, silanes, amines, and heteroaromatics. The gem-disubstituent effect is not required for cyclization. The catalyst is generally regioselective for the anti-Markovnikov product of intermolecular alkyne hydroamination, and chemoselective for hydroamination over C-alkylation when forming 6- and 7-membered rings from aminoalkenes.