54109-95-4

Basic information

• Product Name: Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate
• Synonyms: Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate;2-(3-Pyridinylcarbonyl)butanedioic Acid 1,4-Diethyl Ester;Diethyl 2-(Pyridin-3-ylcarbonyl)succinate
• CAS NO: 54109-95-4
• Molecular Formula: C14H17NO5
• Molecular Weight: 278.28054
• Product Categories: Nicotine Derivatives
• Mol File: 54109-95-4.mol

Chemical Properties

• Boiling Point: 154-156°C @0.7mmHg
• Appearance: /
• Solubility: Chloroform, Ether
• CAS DataBase Reference: Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate(54109-95-4)
• EPA Substance Registry System: Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate(54109-95-4)

Safety Data

• Hazardous Substances Data: 54109-95-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate is used as a synthetic intermediate for the production of various organic compounds. Its chemical properties make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate is used as a key building block for the development of novel drug candidates. Its unique structure allows for the creation of new molecules with potential therapeutic applications, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate is also employed in the agrochemical industry for the synthesis of new compounds with pesticidal, herbicidal, or fungicidal properties. Its incorporation into these compounds can lead to the development of more effective and environmentally friendly agricultural products.
Used in Specialty Chemicals:
In the specialty chemicals sector, Ethyl -Ethoxycarbonyl--oxo-3-pyridinebutyrate is used as a starting material for the synthesis of various high-value chemicals. These can include dyes, fragrances, and other specialty products that require complex molecular structures for their specific applications.

Upstream product

• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 123-25-1 succinic acid diethyl ester 
• 6283-81-4 3-oxo-3-pyridin-3-yl-propionic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 4192-31-8 4-oxo-4-(pyridin-3-yl)butanoic acid 
• 1084874-53-2 C₁₂H₁₃NO₅ 
• 59086-27-0 ethyl 4-oxo-4-(pyridin-3-yl)butanoate 

Relevant articles and documents

Chemoenzymatic and yeast-catalysed synthesis of diastereomeric ethyl γ-phenyl and γ-(n-pyridyl)paraconates

The synthesis of γ-phenyl and γ-(n-pyridyl)paraconates was accomplished by chemical reduction of their respective ketodiester precursors followed by cyclisation of the resulting hydroxy diester intermediates. The cis- and trans-lactones thus obtained were separated and separately subjected to enzymatic hydrolysis with HLAP. The cis-lactonic esters had enantiomeric excesses ranging from 94% to 99%, while for the trans-isomers the ee's ranged from 80% to 93%. The same ketodiester precursors were subjected to reduction with a series of yeasts. The absolute configuration of trans-(-)-2-pyridyl paraconic acid was assigned by means of X-ray analysis of its hydrobromide salt, while the absolute configurations of the other lactones were determined via analysis of their respective CD curves.

Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of γ(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses

The invention concerns the field of synthesis organic chemistry applied to the pharmaceutical field and concerns novel derivatives of 4-hydroxybutanoic acid and its higher homologue, 5-hydroxypentanoic acid, their crotonic homologues, pharmaceutical compo