5422-01-5

Basic information

• Product Name: α-Butylpiperonyl Alcohol
• Synonyms: 1-(1,3-Benzodioxol-5-yl)-1-pentanol;NSC 6605;α-Butyl-1,3-benzodioxole-5-Methanol;α-Butylpiperonyl Alcohol
• CAS NO: 5422-01-5
• Molecular Formula: C12H16O3
• Molecular Weight: 208.25364
• Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics
• Mol File: 5422-01-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 320.9°Cat760mmHg
• Flash Point: 147.9°C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 0.000128mmHg at 25°C
• Refractive Index: 1.546
• Solubility: Chloroform,
• CAS DataBase Reference: α-Butylpiperonyl Alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: α-Butylpiperonyl Alcohol(5422-01-5)
• EPA Substance Registry System: α-Butylpiperonyl Alcohol(5422-01-5)

Safety Data

• Hazardous Substances Data: 5422-01-5(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Intermediate in the preparation of insecticides, fungicides, and other pesticides.

InChI:InChI=1/C12H16O3/c1-2-3-4-10(13)9-5-6-11-12(7-9)15-8-14-11/h5-7,10,13H,2-4,8H2,1H3

Upstream product

• 42930-39-2 n-butylzinc chloride 
• 120-57-0 piperonal 
• 693-04-9 butyl magnesium bromide 
• 109-65-9 1-bromo-butane 
• 109-72-8 n-butyllithium 

Downstream Products

• 687603-66-3 MDPV 
• 63740-98-7 1-(benzo[d]-1,3-dioxol-5-yl)pentan-1-one 
• 146721-06-4 (+/-)-(1R*)-1-Bromo-1-(3,4-methylenedioxybenzoyl)butane 
• 1426578-40-6 N-(1-(benzo[d][1,3]dioxol-5-yl)pentyl)-4-methylbenzenesulfonamide 
• 5432-27-9 1-propanoyloxy-1-(3,4-methylenedioxyphenyl)pentane 

Relevant articles and documents

Direct transformation of aryl 2-pyridyl esters to secondary benzylic alcohols by nickel relay catalysis

A direct transformation of aryl esters to secondary benzylic alcohols via tandem Ni-catalyzed cross-coupling reactions of aromatic 2-pyridyl esters with alkyl zinc reagents and carbonyl group reduction by Ni-H species is achieved. Preliminary mechanistic studies reveal that the Ni-H species is generated in situ via β-hydride elimination of the Negishi reagents. The reaction is catalyzed by bench-stable nickel salts under mild conditions with wide functional group tolerance.

Aromatic amides as potentiators of bioefficacy of anti-infective drugs

The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.

Regioselective annulation of 5-(1-alkenyl)- and 5-vinyl-1,3-benzodioxoles with 3-chloro-3-cyclobutene-1,2-dione. Synthesis of 3,4-dihydrocyclobuta[5,6]-naphtho[2,3-d][1,3]dioxole-1,2-diones and cyclobuta[5,6]naphtho[2,3-d][1,3]dioxole-1,2-diones

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