54262-75-8

Basic information

• Product Name: 1-Azetidinepropanamine
• Synonyms: 1-Azetidinepropanamine;3-(azetidin-1-yl)propan-1-amine
• CAS NO: 54262-75-8
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.18876
• Mol File: 54262-75-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Azetidinepropanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azetidinepropanamine(54262-75-8)
• EPA Substance Registry System: 1-Azetidinepropanamine(54262-75-8)

Safety Data

• Hazardous Substances Data: 54262-75-8(Hazardous Substances Data)

Usage

General Description

1-Azetidinepropanamine, also known as N-Azetidine-3-propanamine or 1-Amino-3-azetidinepropane, is a chemical compound with the molecular formula C5H11N. It is a cyclic amine with a four-membered ring containing one nitrogen atom. 1-Azetidinepropanamine is commonly used as a building block in organic synthesis and pharmaceutical research. It is known for its potential as a key intermediate for the synthesis of various pharmaceutical drugs, such as antiviral and anticancer agents. Additionally, it has been studied for its potential use in the development of new materials and as a reagent in organic chemistry reactions. However, due to its limited commercial availability, it is primarily used in academic and industrial research settings.

Upstream product

• 107128-00-7 N-benzhydryl azetidine 
• 14753-26-5 3-chloropropan-1-amine 
• 503-29-7 azetidine 
• 109-76-2 Trimethylenediamine 

Downstream Products

• 4605-14-5 N,N'-bis-(3-aminopropyl)-1,3-propanediamine 
• 56-18-8 bis(3-aminopropyl)amine 

Relevant articles and documents

KINETICS AND MECHANISM OF CHLOROPROPYLAMINE CYCLIZATIONS

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CATALYTIC ALKYL GROUP EXCHANGE REACTION OF PRIMARY AND SECONDARY AMINES.

It has been shown that primary and secondary amines undergo alkyl group exchange reactions upon treatment with palladium catalyst as depicted in an operationally simple and efficient reaction which provides a convenient method for synthesis of unsymmetrical amines. The application of the reaction for the preparation of various substituted amines and heterocyclic compounds such as hexahydropyrimidine tetrahydropyrimidine, imidazolidine, and imidazoles is described. The preparation of polyamines such as H//2N(CH//2)//mNH(CH//2)//nNH//2 (10) and H//2N(CH//2)//lNH(CH//2)//mNH(CH//2)//nNH//2 (l-n, equals 2,3; 11) is readily performed by the appadium-catalyzed reactions of azetidine (6) and aziridine (7) via azetine (9) and azirine intermediates. The mechanism the palladium-catalyzed reaction has been extensively studied on the carbonylation, racemization, and deuteurium-exchange reaction of (S)-( minus )- alpha -phenylethylamine (17).