54267-47-9

Usage

Uses

Used in Organic Synthesis:
1-(2-Chloroethyl)piperazine hydrochloride is used as a building block in organic synthesis for the creation of various functionalized piperazine derivatives. Its chloroethyl group allows for versatile chemical reactions, enabling the synthesis of a broad range of compounds with diverse applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2-Chloroethyl)piperazine hydrochloride serves as a valuable precursor for the synthesis of potential therapeutic agents. Its unique structure and reactivity make it an attractive candidate for the development of new drugs with improved pharmacological properties.
Used in Pharmaceutical Research:
1-(2-Chloroethyl)piperazine hydrochloride is used as a research compound in pharmaceutical research to explore its potential as a therapeutic agent. Its cytotoxic and antimicrobial properties have been reported, indicating its potential usefulness in the development of new drugs or treatments for cancer and infectious diseases.
Used in Drug Development:
In the drug development industry, 1-(2-Chloroethyl)piperazine hydrochloride is utilized for the discovery and optimization of novel therapeutic agents. Its unique chemical properties and biological activities make it a promising candidate for the treatment of various diseases, including cancer and infectious diseases.

Upstream product

• 103-76-4 1-(2-hydroxyethyl)piperazine 
• 110-85-0 piperazine 
• 107-15-3 ethylenediamine 
• 107-06-2 1,2-dichloro-ethane 
• 5712-71-0 1-(2-hydroxyethyl)piperazine dihydrochloride 

Downstream Products

• 314725-98-9 4,6-Diamino-5-(2-methoxybenzyl)-2-[2-(1-piperazinyl)ethylthio]-pyrimidine 
• 314725-99-0 4,6-Diamino-5-(2-methoxybenzyl)-2-[2-(1-piperazinyl)ethylthio]-pyrimidine fumarate 
• 137554-12-2 Ethyl-(2-piperazin-1-yl-ethyl)-amine 
• 75256-72-3 5-Methyl-2,3-diphenyl-6-[4-(2-piperazin-1-yl-ethoxy)-phenyl]-furo[3,2-g]chromen-7-one 
• 314726-23-3 4,6-Diamino-2-[2-(1-piperazinyl)ethylthio]-5-(4-isopropylbenzyl)-pyrimidine 
• 314726-14-2 4,6-Diamino-2-[2-(4-acetyl-1-piperazinyl)ethylthio]-5-(2-methoxybenzyl)pyrimidine 
• 24028-46-4 1-<2-(2-aminoethyl)aminoethyl>piperazine 
• 19479-83-5 1,2-bis(piperazinyl)-ethane 
• 280-57-9 1,4-diaza-bicyclo[2.2.2]octane 

Relevant academic research and scientific papers

Amine ethylated piperazine and preparation method thereof

The invention provides a preparation method of an amine ethylated piperazine, and relates to the technical field of preparation of aminoethyl piperazine. The method comprises the following steps: mixing a piperazine compound, a chlorination reagent and a soluble piperazine compound solvent to carry out chlorination reaction to obtain the chloropiperazine hydrochloride. The piperazine compound comprises 2 - hydroxyethyl piperazine or N, N' - bis (2 - hydroxyethyl) piperazine. The chloropiperazine hydrochloride, the organic amine and the water are mixed, and the substitution reaction is carried out to obtain the aminated piperazine. The organic amine includes methylamine. Diethylamine, propylamine. The preparation method provided by the invention is high in product yield, high in purity, simple to operate, wide in reaction raw material source, low in production cost and suitable for industrial production.

Cationic polysaccharides and reagents for their preparation

Cationic polysaccharide derivatives are prepared by reacting a polysaccharide with a polycationic reagent having one polysaccharide reactive group and at least two cationic groups. Suitable reagents include polycationic alkyl, aryl, alkaryl, cycloaliphatic, or heterocyclic amines, some of which are novel compositions. The polycationic polysaccharide derivatives prepared from these reagents are useful in the manufacture of paper.