543-83-9 Usage
Uses
Used in Pharmaceutical Industry:
Galegine is used as a potential anti-diabetic agent for its ability to lower blood sugar levels by inhibiting the enzyme glucose-6-phosphatase, which reduces glucose production in the liver.
However, due to its toxic effects on the liver and kidneys at high doses, the use of galegine as a therapeutic agent is limited, and it is primarily a subject of study in the field of natural products and drug development. Further research is needed to explore its potential applications while mitigating its toxic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 543-83-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 543-83:
(5*5)+(4*4)+(3*3)+(2*8)+(1*3)=69
69 % 10 = 9
So 543-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H13N3/c1-5(2)3-4-9-6(7)8/h3H,4H2,1-2H3,(H4,7,8,9)
543-83-9Relevant academic research and scientific papers
Novel hypotensive agents from Verbesina caracasana. 8. Synthesis and pharmacology of (3,4-dimethoxycinnamoyl)-N1-agmatine and synthetic analogues
Carmignani,Volpe,Botta,Espinal,De Bonnevaux,De Luca,Botta,Corelli,Tafi,Sacco,Delle Monache
, p. 2950 - 2958 (2007/10/03)
The more polar metabolites from the Venezuelan plant Verbesina caracasana, i.e., N3-prenylagmatine, (3,4-dimethoxycinnamoyl)-N1-agmatine, agmatine, and galegine (prenylguanidine), previously reported (Delle Monache, G.; et al. BioMed
Amine and amidine containing compounds as weight reducing agents
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, (2008/06/13)
Use of amine and amidine containing compounds of formula (I) such as galegine and related substituted amine and amidine containing compounds as agents for reducing weight in mammals, pharmaceutical formulations containing a compound of formula (I) and methods of attaining weight reduction in mammals.
