5433-78-3

Basic information

• Product Name: 1-[(diphenylmethyl)sulfonyl]-4-methylbenzene
• CAS NO: 5433-78-3
• Molecular Formula: C₂₀H₁₈O₂S
• Molecular Weight: 322.4207
• Mol File: 5433-78-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 512.2°C at 760 mmHg
• Flash Point: 318.6°C
• Density: 1.185g/cm³
• Vapor Pressure: 4.24E-10mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 1-[(diphenylmethyl)sulfonyl]-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(diphenylmethyl)sulfonyl]-4-methylbenzene(5433-78-3)
• EPA Substance Registry System: 1-[(diphenylmethyl)sulfonyl]-4-methylbenzene(5433-78-3)

Safety Data

• Hazardous Substances Data: 5433-78-3(Hazardous Substances Data)

Usage

Appearance

White to off-white crystalline solid

Usage

Reagent in organic synthesis

Derivative of

4-methylbenzyl chloride

Applications

Synthesis of organic compounds, pharmaceuticals, and agrochemicals

Industry relevance

Pharmaceutical and chemical industries

Safety

Handle with care, may be hazardous if not used properly

Upstream product

• 59974-79-7 phthalic acid monobenzhydryl ester 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 90-99-3 diphenylchloromethane 
• 21127-57-1 benzhydryl p-toluenesulfenate 
• 108-86-1 bromobenzene 
• 5395-20-0 1-methyl-4-(benzylsulfonyl)benzene 
• 119-61-9 benzophenone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 91-01-0 1,1-Diphenylmethanol 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 4545-20-4 benzophenone tosylhydrazone 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 5427-07-6 benzhydryl-p-tolyl sulfoxide 

Downstream Products

• 86-29-3 Diphenylacetonitrile 
• 101-81-5 Diphenylmethane 
• 612-00-0 1,1'-ethylidenebis-benzene 
• 4286-85-5 4,4-diphenyl-1-butene 
• 519-73-3 triphenylmethane 
• 530-48-3 1,1-Diphenylethylene 
• 337471-92-8 2-(diphenylmethyl)-5-methylthiophene 

Relevant articles and documents

Visible-Light-Catalyzed in Situ Denitrogenative Sulfonylation of Sulfonylhydrazones

A photocatalyzed in situ denitrogenative sulfonylation of N-arylsulfonyl hydrazones has been developed. This transformation provides a low-carbon strategy to assemble arylalkyl sulfones in a stepwise denitrogenation/sulfonylation manner.

Direct sulfonylation of Baylis-Hillman alcohols and diarylmethanols with TosMIC in ionic liquid-[Hmim]HSO4: An unexpected reaction

A Bronsted acidic ionic liquid-[Hmim]HSO4 promoted unexpected reaction of Baylis-Hillman alcohols and diarylmethanols with p-toluenesulfonylmethyl isocyanide (TosMIC) affording the corresponding sulfone derivatives instead of N-tosylmethyl amid

Iron (III) chloride-catalyzed direct sulfonylation of alcohols with sodium arenesulfinates

A new protocol for the direct sulfonylation of benzylic, allylic and homoallylic alcohols with sodium arenesulfinates is described by using iron (III) chloride as a catalyst and chlorotrimethylsilane as an additive. This method requires no preactivation o