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1-[(diphenylmethyl)sulfonyl]-4-methylbenzene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

5433-78-3

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5433-78-3 Usage

Appearance

White to off-white crystalline solid

Usage

Reagent in organic synthesis

Derivative of

4-methylbenzyl chloride

Applications

Synthesis of organic compounds, pharmaceuticals, and agrochemicals

Industry relevance

Pharmaceutical and chemical industries

Safety

Handle with care, may be hazardous if not used properly

Check Digit Verification of cas no

The CAS Registry Mumber 5433-78-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,3 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5433-78:
(6*5)+(5*4)+(4*3)+(3*3)+(2*7)+(1*8)=93
93 % 10 = 3
So 5433-78-3 is a valid CAS Registry Number.

5433-78-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-benzhydrylsulfonyl-4-methylbenzene

1.2 Other means of identification

Product number -
Other names Diphenylmethyl-p-tolyl-sulfon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5433-78-3 SDS

5433-78-3Relevant academic research and scientific papers

Visible-Light-Catalyzed in Situ Denitrogenative Sulfonylation of Sulfonylhydrazones

Huang, Xiang,Chen, Xing,Xie, Haisheng,Tan, Zheng,Jiang, Huanfeng,Zeng, Wei

supporting information, p. 6784 - 6788 (2021/09/08)

A photocatalyzed in situ denitrogenative sulfonylation of N-arylsulfonyl hydrazones has been developed. This transformation provides a low-carbon strategy to assemble arylalkyl sulfones in a stepwise denitrogenation/sulfonylation manner.

Substrate- and temperature-controlled divergence in reactions of alcohols with TosMIC catalyzed by BF3 · Et2O: Facile access to sulfinates and sulfones

Pogaku, Naresh,Krishna, Palakodety Radha,Prapurna, Y. Lakshmi

supporting information, p. 1239 - 1249 (2017/07/06)

An efficient BF3 · Et2O-catalyzed divergent synthesis of sulfinate esters and sulfones through C–O and C–S bond formation has been achieved from alcohols and p-toluenesulfonylmethyl isocyanide (TosMIC). Various alcohols reacted smoothly with TosMIC under the present conditions at room temperature providing sulfinate esters exclusively. By tuning the reaction temperature, the alcohols that provide highly stabilized carbocation in the reaction medium afforded sulfones as sole products. This study was aimed at understanding the regioselectivity of ambidentate sulfinate ion and to elucidate the interpretation of sulfinate/sulfone scaffolds.

Direct sulfonylation of Baylis-Hillman alcohols and diarylmethanols with TosMIC in ionic liquid-[Hmim]HSO4: An unexpected reaction

Garima,Srivastava, Vishnu P.,Yadav, Lal Dhar S.

experimental part, p. 4622 - 4626 (2011/09/21)

A Bronsted acidic ionic liquid-[Hmim]HSO4 promoted unexpected reaction of Baylis-Hillman alcohols and diarylmethanols with p-toluenesulfonylmethyl isocyanide (TosMIC) affording the corresponding sulfone derivatives instead of N-tosylmethyl amid

Copper-catalyzed nitrogen loss of sulfonylhydrazones: A reductive strategy for the synthesis of sulfones from carbonyl compounds

Feng, Xing-Wen,Wang, Jian,Zhang, Ji,Yang, Jing,Wang, Na,Yu, Xiao-Qi

supporting information; experimental part, p. 4408 - 4411 (2010/12/19)

Figure Presented. An efficient method for the synthesis of sulfones via nitrogen loss of sulfonyl hydrazones is described. The reaction was performed in the presence of simple copper salt and base by utilization of sulfonyl hydrazones, which were easily p

Iron (III) chloride-catalyzed direct sulfonylation of alcohols with sodium arenesulfinates

Reddy, M. Amarnath,Reddy, P. Surendra,Sreedhar

supporting information; experimental part, p. 1861 - 1869 (2010/10/21)

A new protocol for the direct sulfonylation of benzylic, allylic and homoallylic alcohols with sodium arenesulfinates is described by using iron (III) chloride as a catalyst and chlorotrimethylsilane as an additive. This method requires no preactivation o

Palladium-catalyzed benzylic direct arylation of benzyl sulfones with aryl halides

Niwa, Takashi,Yorimitsu, Hideki,Oshima, Koichiro

experimental part, p. 1971 - 1976 (2009/08/07)

An effective palladium catalyst system for the direct arylation of benzyl sulfones with aryl halides has been developed. The catalytic reaction provides a facile route to diarylmethyl sulfones. The products can be transformed further via desulfonylative functionalization mediated by aluminum compounds.

Studies of Sulfinyl Radicals. 1. Thermal Decompositions of Benzhydryl p-Tolyl Sulfoxide and Benzhydryl Methyl Sulfoxide

Mizuno, Hajime,Matsuda, Minoru,Iino, Masashi

, p. 520 - 525 (2007/10/02)

The kinetics and mechanism of the thermal decompositions of benzhydryl p-tolyl sulfoxide (BTSO) and benzhydryl methyl sulfoxide (BMSO) were studied.Product analysis, ESR, and CIDNP results showed that both sulfoxides gave p-toluenesulfinyl and methanesulfinyl radicals, respectively, by the scission of carbon-sulfur bonds at 100-130 deg C.The presence of a small amount of a base such as pyridine has been found to suppress the formation of other products than the coupling products (the corresponding thiosulfonates and tetraphenylethane), which may be formed by ionic reactions of BTSO and BMSO.The mechanism of BTSO decomposition is complex, since it is in equilibrium with benzhydryl p-toluenesulfenate (BTSN) at 100-130 deg C.On the other hand, BMSO, showing simple decomposition behavior, indicated that the decomposition rates decreased on the addition of hydroxylic solvents.

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