54433-51-1

Basic information

• Product Name: 2,5-Pyrrolidinedione, 3-phenyl-1-(2-propenyl)-
• CAS NO: 54433-51-1
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Mol File: 54433-51-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 3-phenyl-1-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 3-phenyl-1-(2-propenyl)-(54433-51-1)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 3-phenyl-1-(2-propenyl)-(54433-51-1)

Safety Data

• Hazardous Substances Data: 54433-51-1(Hazardous Substances Data)

Upstream product

• 635-51-8 2-phenylsuccinic acid 
• 107-11-9 1-amino-2-propene 
• 1131-15-3 2-phenylsuccinic anhydride 
• 2973-17-3 N-allylmaleic imide 
• 65-85-0 benzoic acid 

Relevant articles and documents

Ruthenium(II)-Catalyzed Hydroarylation of Maleimides Using Carboxylic Acids as a Traceless Directing Group

An efficient Ru(II)-catalyzed hydroarylation of maleimides with ready-stock aryl carboxylic acids has been developed based on weak carboxylate-directed ortho-C-H alkylation and concomitant decarboxylation processes, fabricating 3-aryl succinimides, a recurrent scaffold in drug molecules, in high yields (up to 97%). The protocol features operational simplicity, avoids the need for precious metal additives/oxidants, and offers broad substrate scope with formal meta- and para-selectivities. It represents the first example of Ru(II)-catalyzed direct arylation of maleimides with unbiased benzoic acids.